Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-12-09 | Massachusetts (182) | 0 | 0 | La Salle (237) | Postponed | - | - |
| 2 | 2020-12-11 | Northeastern (300) | 79 | 94 | Massachusetts (182) | Final | W | 15 |
| 3 | 2020-12-13 | Massachusetts (182) | 75 | 78 | Northeastern (300) | Final | L | -3 |
| 4 | 2020-12-16 | Massachusetts (182) | 85 | 66 | La Salle (237) | Final | W | 19 |
| 5 | 2020-12-21 | Bryant (349) | 93 | 88 | Massachusetts (182) | Final | L | -5 |
| 6 | 2020-12-30 | George Mason (86) | 93 | 92 | Massachusetts (182) | Final/2OT | L | -1 |
| 7 | 2021-01-02 | Massachusetts (182) | 0 | 0 | Saint Louis (31) | Postponed | - | - |
| 8 | 2021-01-06 | Massachusetts (182) | 0 | 0 | George Washington (104) | Cancelled | - | - |
| 9 | 2021-01-09 | La Salle (237) | 67 | 83 | Massachusetts (182) | Final | W | 16 |
| 10 | 2021-01-13 | Rhode Island (145) | 78 | 80 | Massachusetts (182) | Final/OT | W | 2 |
| 11 | 2021-01-17 | Massachusetts (182) | 65 | 46 | Fordham (183) | Final | W | 19 |
| 12 | 2021-01-20 | Saint Louis (31) | 0 | 0 | Massachusetts (182) | Cancelled | - | - |
| 13 | 2021-01-24 | Davidson (111) | 69 | 60 | Massachusetts (182) | Final | L | -9 |
| 14 | 2021-01-27 | Massachusetts (182) | 0 | 0 | Virginia Commonwealth (38) | Cancelled | - | - |
| 15 | 2021-01-30 | Massachusetts (118) | 0 | 0 | George Mason (172) | Cancelled | - | - |
| 16 | 2021-02-03 | Fordham (183) | 54 | 60 | Massachusetts (182) | Final | W | 6 |
| 17 | 2021-02-06 | Massachusetts (182) | 75 | 63 | Rhode Island (145) | Final | W | 12 |
| 18 | 2021-02-09 | Dayton | 0 | 0 | Massachusetts | Cancelled | - | - |
| 19 | 2021-02-12 | Massachusetts | 0 | 0 | Virginia Commonwealth | Cancelled | - | - |
| 20 | 2021-02-14 | St. Bonaventure (146) | 0 | 0 | Massachusetts (182) | Cancelled | - | - |
| 21 | 2021-02-23 | Massachusetts (182) | 65 | 79 | Richmond (166) | Final | L | -14 |
| 22 | 2021-02-24 | Massachusetts | 0 | 0 | Saint Joseph's | Cancelled | - | - |
| 23 | 2021-02-27 | Massachusetts (182) | 0 | 0 | Saint Louis (31) | Postponed | - | - |
| 24 | 2021-03-01 | Massachusetts (123) | 57 | 78 | Saint Louis (67) | Final | L | -21 |
| 25 | 2021-03-04 | Saint Joseph's (99) | 66 | 100 | Massachusetts (182) | Final | W | 34 |
| 26 | 2021-03-05 | Massachusetts (182) | 72 | 86 | Saint Louis (31) | Final | L | -14 |