Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2019-11-05 | Louisville (26) | 87 | 74 | Miami (88) | Final | W | 13 |
| 2 | 2019-11-10 | Youngstown State (275) | 55 | 78 | Louisville (26) | Final | W | 23 |
| 3 | 2019-11-13 | Indiana State (188) | 62 | 91 | Louisville (26) | Final | W | 29 |
| 4 | 2019-11-17 | North Carolina Central (288) | 58 | 87 | Louisville (26) | Final | W | 29 |
| 5 | 2019-11-20 | South Carolina Upstate (313) | 50 | 76 | Louisville (13) | Final | W | 26 |
| 6 | 2019-11-24 | Akron (189) | 76 | 82 | Louisville (13) | Final | W | 6 |
| 7 | 2019-11-29 | Louisville (12) | 71 | 54 | Western Kentucky (82) | Final | W | 17 |
| 8 | 2019-12-03 | Michigan (3) | 43 | 58 | Louisville (16) | Final | W | 15 |
| 9 | 2019-12-06 | Pittsburgh (72) | 46 | 64 | Louisville (16) | Final | W | 18 |
| 10 | 2019-12-10 | Texas Tech (89) | 70 | 57 | Louisville (3) | Final | L | -13 |
| 11 | 2019-12-14 | Eastern Kentucky (301) | 67 | 99 | Louisville (3) | Final | W | 32 |
| 12 | 2019-12-18 | Miami (OH) (226) | 46 | 70 | Louisville (11) | Final | W | 24 |
| 13 | 2019-12-28 | Louisville (10) | 70 | 78 | Kentucky (62) | Final (OT) | L | -8 |
| 14 | 2020-01-04 | Florida State (23) | 78 | 65 | Louisville (17) | Final | L | -13 |
| 15 | 2020-01-07 | Miami (71) | 58 | 74 | Louisville (22) | Final | W | 16 |
| 16 | 2020-01-11 | Louisville (22) | 67 | 64 | Notre Dame (81) | Final | W | 3 |
| 17 | 2020-01-14 | Louisville (17) | 73 | 68 | Pittsburgh (71) | Final (OT) | W | 5 |
| 18 | 2020-01-18 | Louisville (17) | 79 | 73 | Duke (1) | Final | W | 6 |
| 19 | 2020-01-22 | Georgia Tech (103) | 64 | 68 | Louisville (9) | Final | W | 4 |
| 20 | 2020-01-25 | Clemson (81) | 62 | 80 | Louisville (9) | Final | W | 18 |
| 21 | 2020-01-29 | Louisville (10) | 86 | 69 | Boston College (128) | Final | W | 17 |
| 22 | 2020-02-01 | Louisville (10) | 77 | 57 | North Carolina State (47) | Final | W | 20 |
| 23 | 2020-02-05 | Wake Forest (105) | 76 | 86 | Louisville (7) | Final | W | 10 |
| 24 | 2020-02-08 | Virginia (50) | 73 | 80 | Louisville (7) | Final | W | 7 |
| 25 | 2020-02-12 | Louisville (7) | 58 | 64 | Georgia Tech (94) | Final | L | -6 |
| 26 | 2020-02-15 | Louisville (7) | 62 | 77 | Clemson (90) | Final | L | -15 |
| 27 | 2020-02-19 | Syracuse (62) | 66 | 90 | Louisville (13) | Final | W | 24 |
| 28 | 2020-02-22 | North Carolina (99) | 55 | 72 | Louisville (13) | Final | W | 17 |
| 29 | 2020-02-24 | Louisville (13) | 67 | 82 | Florida State (10) | Final | L | -15 |
| 30 | 2020-03-01 | Virginia Tech (85) | 52 | 68 | Louisville (10) | Final | W | 16 |
| 31 | 2020-03-07 | Louisville (10) | 54 | 57 | Virginia (29) | Final | L | -3 |
| 32 | 2020-03-12 | Syracuse (84) | 0 | 0 | Louisville (21) | Cancelled | - | - |