Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2019-11-05 | Virginia Tech (16) | 67 | 60 | Clemson (47) | Final | L | -7 |
| 2 | 2019-11-07 | Presbyterian (208) | 45 | 79 | Clemson (47) | Final | W | 34 |
| 3 | 2019-11-10 | Colgate (133) | 68 | 81 | Clemson (47) | Final | W | 13 |
| 4 | 2019-11-17 | Detroit (248) | 65 | 87 | Clemson (47) | Final | W | 22 |
| 5 | 2019-11-21 | Alabama A&M (349) | 51 | 87 | Clemson (70) | Final | W | 36 |
| 6 | 2019-11-24 | TCU (85) | 60 | 62 | Clemson (70) | Final/OT | W | 2 |
| 7 | 2019-11-26 | Colorado (21) | 71 | 67 | Clemson (59) | Final | L | -4 |
| 8 | 2019-12-02 | Clemson (59) | 60 | 78 | Minnesota (102) | Final | L | -18 |
| 9 | 2019-12-08 | Clemson (64) | 53 | 72 | Florida State (15) | Final | L | -19 |
| 10 | 2019-12-15 | South Carolina (132) | 67 | 54 | Clemson (107) | Final | L | -13 |
| 11 | 2019-12-20 | Jacksonville (207) | 39 | 68 | Clemson (126) | Final | W | 29 |
| 12 | 2019-12-22 | Yale (65) | 54 | 45 | Clemson (126) | Final | L | -9 |
| 13 | 2019-12-31 | Miami (72) | 73 | 68 | Clemson (107) | Final (OT) | L | -5 |
| 14 | 2020-01-04 | North Carolina State (37) | 70 | 81 | Clemson (107) | Final | W | 11 |
| 15 | 2020-01-11 | Clemson (103) | 79 | 76 | North Carolina (84) | Final (OT) | W | 3 |
| 16 | 2020-01-14 | Duke (1) | 72 | 79 | Clemson (87) | Final | W | 7 |
| 17 | 2020-01-18 | Clemson (87) | 54 | 60 | North Carolina State (61) | Final | L | -6 |
| 18 | 2020-01-21 | Wake Forest (99) | 68 | 71 | Clemson (81) | Final | W | 3 |
| 19 | 2020-01-25 | Clemson (81) | 62 | 80 | Louisville (9) | Final | L | -18 |
| 20 | 2020-01-28 | Syracuse (84) | 70 | 71 | Clemson (36) | Final | W | 1 |
| 21 | 2020-02-01 | Clemson (76) | 44 | 56 | Wake Forest (110) | Final | L | -12 |
| 22 | 2020-02-05 | Clemson (83) | 44 | 51 | Virginia (50) | Final | L | -7 |
| 23 | 2020-02-09 | Notre Dame (74) | 61 | 57 | Clemson (83) | Final | L | -4 |
| 24 | 2020-02-12 | Clemson (90) | 72 | 52 | Pittsburgh (63) | Final | W | 20 |
| 25 | 2020-02-15 | Louisville (7) | 62 | 77 | Clemson (90) | Final | W | 15 |
| 26 | 2020-02-22 | Clemson (71) | 82 | 64 | Boston College (116) | Final | W | 18 |
| 27 | 2020-02-25 | Clemson (66) | 59 | 68 | Georgia Tech (91) | Final | L | -9 |
| 28 | 2020-02-29 | Florida State (8) | 69 | 70 | Clemson (66) | Final | W | 1 |
| 29 | 2020-03-04 | Clemson (65) | 58 | 70 | Virginia Tech (89) | Final | L | -12 |
| 30 | 2020-03-06 | Georgia Tech (84) | 65 | 62 | Clemson (65) | Final | L | -3 |
| 31 | 2020-03-11 | Miami (90) | 64 | 69 | Clemson (80) | Final | W | 5 |
| 32 | 2020-03-12 | Clemson (36) | 0 | 0 | Florida State (64) | Cancelled | - | - |