Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-12-03 | Louisiana-Monroe (358) | 62 | 78 | Louisiana Tech (185) | Final | L | -16 |
| 2 | 2020-12-06 | Louisiana-Monroe (358) | 92 | 83 | Northwestern State (315) | Final/OT | W | 9 |
| 3 | 2020-12-09 | Lamar (279) | 63 | 60 | Louisiana-Monroe (358) | Final | L | -3 |
| 4 | 2020-12-12 | Stephen F. Austin (88) | 55 | 66 | Louisiana-Monroe (358) | Final | W | 11 |
| 5 | 2020-12-16 | Grambling (312) | 78 | 61 | Louisiana-Monroe (358) | Final | L | -17 |
| 6 | 2020-12-19 | Louisiana-Monroe (358) | 47 | 60 | Southern Miss (201) | Final | L | -13 |
| 7 | 2020-12-22 | Louisiana Tech (185) | 68 | 57 | Louisiana-Monroe (358) | Final | L | -11 |
| 8 | 2021-01-01 | Arkansas State (147) | 72 | 84 | Louisiana-Monroe (358) | Final | W | 12 |
| 9 | 2021-01-02 | Arkansas State (147) | 55 | 62 | Louisiana-Monroe (358) | Final | W | 7 |
| 10 | 2021-01-08 | Texas-Arlington (162) | 77 | 64 | Louisiana-Monroe (358) | Final | L | -13 |
| 11 | 2021-01-09 | Texas-Arlington (162) | 75 | 74 | Louisiana-Monroe (358) | Final | L | -1 |
| 12 | 2021-01-15 | Louisiana-Monroe (358) | 72 | 74 | Arkansas State (147) | Final | L | -2 |
| 13 | 2021-01-16 | Louisiana-Monroe (358) | 72 | 93 | Arkansas State (147) | Final | L | -21 |
| 14 | 2021-01-22 | Texas State (199) | 57 | 47 | Louisiana-Monroe (358) | Final | L | -10 |
| 15 | 2021-01-23 | Texas State (199) | 69 | 63 | Louisiana-Monroe (358) | Final | L | -6 |
| 16 | 2021-01-29 | Louisiana-Monroe (358) | 62 | 66 | Little Rock (321) | Final | L | -4 |
| 17 | 2021-01-30 | Louisiana-Monroe (358) | 49 | 65 | Little Rock (321) | Final | L | -16 |
| 18 | 2021-02-05 | Louisiana-Monroe (358) | 56 | 63 | Texas-Arlington (162) | Final | L | -7 |
| 19 | 2021-02-06 | Louisiana-Monroe (358) | 52 | 58 | Texas-Arlington (162) | Final | L | -6 |
| 20 | 2021-02-11 | Louisiana-Monroe (358) | 72 | 66 | Louisiana (290) | Final | W | 6 |
| 21 | 2021-02-13 | Louisiana (290) | 88 | 72 | Louisiana-Monroe (358) | Final | L | -16 |
| 22 | 2021-02-21 | Little Rock (321) | 66 | 78 | Louisiana-Monroe (358) | Final | W | 12 |
| 23 | 2021-02-22 | Little Rock (321) | 64 | 68 | Louisiana-Monroe (358) | Final | W | 4 |
| 24 | 2021-02-26 | Louisiana-Monroe (358) | 49 | 58 | Texas State (199) | Final | L | -9 |
| 25 | 2021-02-27 | Louisiana-Monroe (358) | 57 | 61 | Texas State (199) | Final | L | -4 |
| 26 | 2021-03-05 | Louisiana-Monroe (358) | 72 | 80 | South Alabama (177) | Final | L | -8 |