Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Abilene Christian (245) | 70 | 47 | East Tennessee State (140) | Final | L | -23 |
| 2 | 2020-11-25 | East Tennessee State (33) | 47 | 70 | Abilene Christian (188) | Final | L | -23 |
| 3 | 2020-11-26 | Austin Peay (138) | 67 | 66 | East Tennessee State (140) | Final | L | -1 |
| 4 | 2020-11-27 | East Tennessee State (140) | 57 | 43 | Middle Tennessee (164) | Final | W | 14 |
| 5 | 2020-12-08 | East Tennessee State (140) | 0 | 0 | UNC-Asheville (244) | Cancelled | - | - |
| 6 | 2020-12-12 | UAB (115) | 65 | 61 | East Tennessee State (140) | Final | L | -4 |
| 7 | 2020-12-15 | North Carolina A&T (342) | 0 | 0 | East Tennessee State (233) | Cancelled | - | - |
| 8 | 2020-12-15 | Gardner-Webb (363) | 60 | 65 | East Tennessee State (140) | Final | W | 5 |
| 9 | 2020-12-17 | Virginia-Wise | 0 | 0 | East Tennessee State (233) | Cancelled | - | - |
| 10 | 2020-12-17 | Columbia International | 54 | 96 | East Tennessee State (140) | Final | W | 42 |
| 11 | 2020-12-18 | Virginia-Wise | 0 | 0 | East Tennessee State (140) | Cancelled | - | - |
| 12 | 2020-12-19 | Lee | 53 | 62 | East Tennessee State (233) | Final | W | 9 |
| 13 | 2020-12-22 | East Tennessee State (140) | 69 | 85 | Alabama (15) | Final | L | -16 |
| 14 | 2020-12-30 | Western Carolina (223) | 78 | 86 | East Tennessee State (140) | Final | W | 8 |
| 15 | 2021-01-02 | East Tennessee State (140) | 71 | 61 | UNC-Greensboro (265) | Final | W | 10 |
| 16 | 2021-01-06 | Virginia Military (230) | 0 | 0 | East Tennessee State (160) | Cancelled | - | - |
| 17 | 2021-01-09 | East Tennessee State (160) | 0 | 0 | Wofford (93) | Cancelled | - | - |
| 18 | 2021-01-13 | Samford (172) | 0 | 0 | East Tennessee State (152) | Cancelled | - | - |
| 19 | 2021-01-16 | East Tennessee State (140) | 66 | 78 | Furman (157) | Final | L | -12 |
| 20 | 2021-01-18 | Virginia Military (357) | 81 | 92 | East Tennessee State (140) | Final | W | 11 |
| 21 | 2021-01-20 | East Tennessee State (140) | 59 | 48 | Western Carolina (223) | Final | W | 11 |
| 22 | 2021-01-23 | Furman (157) | 62 | 71 | East Tennessee State (140) | Final | W | 9 |
| 23 | 2021-01-27 | Chattanooga (291) | 0 | 0 | East Tennessee State (140) | Postponed | - | - |
| 24 | 2021-01-30 | The Citadel (332) | 84 | 112 | East Tennessee State (140) | Final | W | 28 |
| 25 | 2021-02-01 | Samford (208) | 0 | 0 | East Tennessee State (121) | Cancelled | - | - |
| 26 | 2021-02-01 | East Tennessee State (140) | 62 | 67 | Wofford (221) | Final | L | -5 |
| 27 | 2021-02-03 | East Tennessee State (140) | 70 | 64 | Mercer (174) | Final | W | 6 |
| 28 | 2021-02-06 | Chattanooga (291) | 67 | 65 | East Tennessee State (140) | Final | L | -2 |
| 29 | 2021-02-10 | East Tennessee State (140) | 71 | 79 | The Citadel (332) | Final | L | -8 |
| 30 | 2021-02-13 | Wofford (221) | 49 | 71 | East Tennessee State (140) | Final | W | 22 |
| 31 | 2021-02-15 | East Tennessee State (140) | 51 | 53 | Chattanooga (291) | Final | L | -2 |
| 32 | 2021-02-17 | Mercer (174) | 71 | 64 | East Tennessee State (140) | Final | L | -7 |
| 33 | 2021-02-20 | East Tennessee State (140) | 0 | 0 | Samford (203) | Cancelled | - | - |
| 34 | 2021-02-24 | East Tennessee State (140) | 0 | 0 | Virginia Military (357) | Cancelled | - | - |
| 35 | 2021-02-27 | UNC-Greensboro (265) | 85 | 74 | East Tennessee State (140) | Final/OT | L | -11 |
| 36 | 2021-03-06 | East Tennessee State (140) | 63 | 53 | Chattanooga (291) | Final | W | 10 |
| 37 | 2021-03-07 | East Tennessee State (140) | 65 | 77 | UNC-Greensboro (265) | Final | L | -12 |