Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2024-11-04 | Chattanooga (291) | 51 | 77 | USC (71) | Final | W | 26 |
| 2 | 2024-11-07 | Idaho State (289) | 69 | 75 | USC (71) | Final | W | 6 |
| 3 | 2024-11-13 | Texas-Arlington (286) | 95 | 98 | USC (78) | Final | W | 3 |
| 4 | 2024-11-17 | California (45) | 71 | 66 | USC (94) | Final | L | -5 |
| 5 | 2024-11-20 | San Jose State (229) | 68 | 82 | USC (71) | Final | W | 14 |
| 6 | 2024-11-24 | Grambling (258) | 69 | 80 | USC (88) | Final | W | 11 |
| 7 | 2024-11-28 | Saint Mary's (14) | 71 | 36 | USC (95) | Final | L | -35 |
| 8 | 2024-11-30 | USC (110) | 73 | 83 | New Mexico (55) | Final | L | -10 |
| 9 | 2024-12-04 | Oregon (18) | 68 | 60 | USC (85) | Final | L | -8 |
| 10 | 2024-12-07 | USC (99) | 85 | 61 | Washington (117) | Final | W | 24 |
| 11 | 2024-12-15 | Montana State (190) | 63 | 89 | USC (95) | Final | W | 26 |
| 12 | 2024-12-18 | Cal State-Northridge (154) | 69 | 90 | USC (83) | Final | W | 21 |
| 13 | 2024-12-22 | Southern (239) | 51 | 82 | USC (78) | Final | W | 31 |
| 14 | 2025-01-04 | Michigan (21) | 85 | 74 | USC (80) | Final | L | -11 |
| 15 | 2025-01-08 | USC (86) | 69 | 82 | Indiana (33) | Final | L | -13 |
| 16 | 2025-01-11 | USC (73) | 82 | 72 | Illinois (20) | Final | W | 10 |
| 17 | 2025-01-14 | Iowa (41) | 89 | 99 | USC (60) | Final | W | 10 |
| 18 | 2025-01-18 | Wisconsin (19) | 84 | 69 | USC (64) | Final | L | -15 |
| 19 | 2025-01-22 | USC (61) | 78 | 73 | Nebraska (56) | Final | W | 5 |
| 20 | 2025-01-27 | UCLA (37) | 82 | 76 | USC (66) | Final | L | -6 |
| 21 | 2025-02-01 | Michigan State (11) | 64 | 70 | USC (53) | Final | W | 6 |
| 22 | 2025-02-04 | USC (57) | 75 | 77 | Northwestern (60) | Final | L | -2 |
| 23 | 2025-02-07 | USC (60) | 72 | 90 | Purdue (7) | Final | L | -18 |
| 24 | 2025-02-11 | Penn State (78) | 67 | 92 | USC (55) | Final | W | 25 |
| 25 | 2025-02-15 | Minnesota (77) | 69 | 66 | USC (59) | Final | L | -3 |
| 26 | 2025-02-20 | USC (59) | 71 | 88 | Maryland (17) | Final | L | -17 |
| 27 | 2025-02-23 | USC (64) | 85 | 95 | Rutgers (74) | Final | L | -10 |
| 28 | 2025-02-26 | Ohio State (41) | 87 | 82 | USC (67) | Final | L | -5 |
| 29 | 2025-03-01 | USC (71) | 61 | 82 | Oregon (102) | Final | L | -21 |
| 30 | 2025-03-05 | Washington (105) | 61 | 92 | USC (66) | Final | W | 31 |
| 31 | 2025-03-08 | USC (71) | 63 | 90 | UCLA (26) | Final | L | -27 |
| 32 | 2025-03-12 | USC (67) | 97 | 89 | Rutgers (77) | Final (2OT) | W | 8 |
| 33 | 2025-03-13 | USC (67) | 71 | 76 | Purdue (18) | Final | L | -5 |
| 34 | 2025-04-01 | Tulane (150) | 60 | 89 | USC (67) | Final | W | 29 |
| 35 | 2025-04-03 | Villanova (68) | 60 | 59 | USC (67) | Final | L | -1 |