Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Southern Indiana (265) | 91 | 97 | Missouri (38) | Final | L | -6 |
| 2 | 2022-11-13 | Southern Illinois (113) | 53 | 71 | Southern Indiana (265) | Final | W | 18 |
| 3 | 2022-11-16 | Southern Indiana (265) | 70 | 82 | Notre Dame (199) | Final | L | -12 |
| 4 | 2022-11-18 | Loras | 55 | 87 | Southern Indiana (265) | Final | W | 32 |
| 5 | 2022-11-22 | Southern Indiana (265) | 66 | 80 | St. Bonaventure (171) | Final | L | -14 |
| 6 | 2022-11-26 | Southern Indiana (265) | 69 | 57 | Bowling Green (290) | Final | W | 12 |
| 7 | 2022-11-30 | Southern Indiana (352) | 78 | 86 | Western Illinois (362) | Final | L | -8 |
| 8 | 2022-12-04 | Southern Indiana (265) | 61 | 78 | Chicago State (323) | Final | L | -17 |
| 9 | 2022-12-07 | Anderson (IN) | 47 | 78 | Southern Indiana (265) | Final | W | 31 |
| 10 | 2022-12-11 | Indiana State (114) | 85 | 88 | Southern Indiana (265) | Final | W | 3 |
| 11 | 2022-12-15 | Saint Mary-of-the-Woods | 42 | 84 | Southern Indiana (265) | Final | W | 42 |
| 12 | 2022-12-19 | Southern Indiana (352) | 87 | 74 | IU-Indy (338) | Final | W | 13 |
| 13 | 2022-12-19 | Southern Indiana (265) | 87 | 74 | IUPUI (362) | Final | W | 13 |
| 14 | 2022-12-20 | Southern Indiana (265) | 59 | 83 | Purdue Fort Wayne (213) | Final | L | -24 |
| 15 | 2022-12-29 | Southeast Missouri State (226) | 81 | 86 | Southern Indiana (352) | Final | W | 5 |
| 16 | 2022-12-31 | Southern Indiana (265) | 80 | 91 | Eastern Illinois (341) | Final | L | -11 |
| 17 | 2023-01-05 | Southern Indiana (265) | 80 | 84 | Morehead State (212) | Final | L | -4 |
| 18 | 2023-01-07 | SIU-Edwardsville (241) | 69 | 62 | Southern Indiana (265) | Final | L | -7 |
| 19 | 2023-01-12 | Little Rock (345) | 67 | 74 | Southern Indiana (265) | Final | W | 7 |
| 20 | 2023-01-14 | Tennessee-Martin (237) | 66 | 80 | Southern Indiana (265) | Final | W | 14 |
| 21 | 2023-01-19 | Southern Indiana (265) | 81 | 65 | Lindenwood (347) | Final | W | 16 |
| 22 | 2023-01-21 | Southern Indiana (265) | 82 | 72 | SIU-Edwardsville (241) | Final | W | 10 |
| 23 | 2023-01-26 | Eastern Illinois (341) | 74 | 78 | Southern Indiana (265) | Final | W | 4 |
| 24 | 2023-01-28 | Southern Indiana (265) | 83 | 86 | Tennessee-Martin (237) | Final | L | -3 |
| 25 | 2023-02-02 | Tennessee State (266) | 80 | 76 | Southern Indiana (265) | Final | L | -4 |
| 26 | 2023-02-04 | Morehead State (212) | 71 | 66 | Southern Indiana (265) | Final | L | -5 |
| 27 | 2023-02-09 | Southern Indiana (265) | 69 | 84 | Tennessee Tech (288) | Final | L | -15 |
| 28 | 2023-02-11 | Lindenwood (247) | 64 | 74 | Southern Indiana (352) | Final | W | 10 |
| 29 | 2023-02-16 | Southern Indiana (265) | 82 | 81 | Little Rock (345) | Final | W | 1 |
| 30 | 2023-02-18 | Southern Indiana (352) | 80 | 85 | Southeast Missouri State (226) | Final | L | -5 |
| 31 | 2023-02-23 | Tennessee Tech (310) | 82 | 79 | Southern Indiana (352) | Final | L | -3 |
| 32 | 2023-02-25 | Southern Indiana (265) | 93 | 81 | Tennessee State (267) | Final | W | 12 |
| 33 | 2023-03-01 | Southern Indiana (352) | 54 | 68 | SIU-Edwardsville (248) | Final | L | -14 |
| 34 | 2023-03-18 | San Jose State (90) | 77 | 52 | Southern Indiana (270) | Final | L | -25 |