Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Harris Stowe | 57 | 85 | SIU-Edwardsville (241) | Final | W | 28 |
| 2 | 2022-11-12 | SIU-Edwardsville (241) | 76 | 81 | Purdue Fort Wayne (213) | Final | L | -5 |
| 3 | 2022-11-15 | SIU-Edwardsville (241) | 80 | 105 | Missouri (38) | Final | L | -25 |
| 4 | 2022-11-18 | Fairleigh-Dickinson (286) | 78 | 79 | SIU-Edwardsville (241) | Final | W | 1 |
| 5 | 2022-11-19 | SIU-Edwardsville (241) | 93 | 67 | Virginia Military (355) | Final | W | 26 |
| 6 | 2022-11-20 | SIU-Edwardsville (241) | 61 | 56 | Longwood (180) | Final | W | 5 |
| 7 | 2022-11-26 | SIU-Edwardsville (241) | 64 | 54 | UMKC (282) | Final | W | 10 |
| 8 | 2022-11-29 | St. Ambrose | 54 | 89 | SIU-Edwardsville (241) | Final | W | 35 |
| 9 | 2022-12-03 | Troy (148) | 72 | 78 | SIU-Edwardsville (241) | Final | W | 6 |
| 10 | 2022-12-06 | Bradley (79) | 56 | 54 | SIU-Edwardsville (241) | Final | L | -2 |
| 11 | 2022-12-10 | SIU-Edwardsville (241) | 71 | 77 | Illinois State (263) | Final | L | -6 |
| 12 | 2022-12-16 | Chicago State | 0 | 0 | SIU-Edwardsville | Scheduled - TBA | - | - |
| 13 | 2022-12-21 | SIU-Edwardsville (241) | 69 | 67 | Saint Louis (80) | Final | W | 2 |
| 14 | 2022-12-29 | Tennessee Tech (288) | 51 | 64 | SIU-Edwardsville (241) | Final | W | 13 |
| 15 | 2022-12-31 | SIU-Edwardsville (241) | 73 | 82 | Southeast Missouri State (250) | Final | L | -9 |
| 16 | 2023-01-05 | Tennessee State (266) | 72 | 81 | SIU-Edwardsville (241) | Final | W | 9 |
| 17 | 2023-01-07 | SIU-Edwardsville (241) | 69 | 62 | Southern Indiana (265) | Final | W | 7 |
| 18 | 2023-01-12 | SIU-Edwardsville (241) | 80 | 62 | Eastern Illinois (341) | Final | W | 18 |
| 19 | 2023-01-14 | Lindenwood (347) | 58 | 68 | SIU-Edwardsville (241) | Final | W | 10 |
| 20 | 2023-01-19 | Morehead State (212) | 67 | 58 | SIU-Edwardsville (241) | Final | L | -9 |
| 21 | 2023-01-21 | Southern Indiana (265) | 82 | 72 | SIU-Edwardsville (241) | Final | L | -10 |
| 22 | 2023-01-26 | SIU-Edwardsville (241) | 68 | 80 | Tennessee Tech (288) | Final | L | -12 |
| 23 | 2023-01-28 | SIU-Edwardsville (241) | 50 | 55 | Morehead State (212) | Final | L | -5 |
| 24 | 2023-02-02 | Tennessee-Martin (237) | 75 | 89 | SIU-Edwardsville (241) | Final | W | 14 |
| 25 | 2023-02-04 | SIU-Edwardsville (241) | 84 | 81 | Little Rock (345) | Final | W | 3 |
| 26 | 2023-02-09 | SIU-Edwardsville (241) | 63 | 58 | Lindenwood (347) | Final | W | 5 |
| 27 | 2023-02-11 | Eastern Illinois (341) | 84 | 73 | SIU-Edwardsville (241) | Final | L | -11 |
| 28 | 2023-02-16 | SIU-Edwardsville (241) | 84 | 90 | Tennessee-Martin (237) | Final | L | -6 |
| 29 | 2023-02-18 | SIU-Edwardsville (241) | 85 | 100 | Tennessee State (266) | Final | L | -15 |
| 30 | 2023-02-23 | Little Rock (335) | 79 | 74 | SIU-Edwardsville (246) | Final | L | -5 |
| 31 | 2023-02-25 | Southeast Missouri State (263) | 78 | 93 | SIU-Edwardsville (239) | Final | W | 15 |
| 32 | 2023-03-01 | Southern Indiana (268) | 54 | 68 | SIU-Edwardsville (232) | Final | W | 14 |
| 33 | 2023-03-02 | SIU-Edwardsville (227) | 75 | 81 | Tennessee-Martin (253) | Final | L | -6 |