Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-11-03 | McKendree | 42 | 83 | Southern Illinois (187) | Final | W | 41 |
| 2 | 2025-11-07 | UMKC (275) | 78 | 101 | Southern Illinois (187) | Final | W | 23 |
| 3 | 2025-11-12 | Southern Illinois (187) | 81 | 86 | Nevada (97) | Final/OT | L | -5 |
| 4 | 2025-11-17 | Southern Illinois (187) | 85 | 92 | North Dakota State (162) | Final | L | -7 |
| 5 | 2025-11-23 | Southern Illinois (187) | 79 | 59 | Delaware (238) | Final | W | 20 |
| 6 | 2025-11-24 | UAB (99) | 81 | 73 | Southern Illinois (187) | Final | L | -8 |
| 7 | 2025-11-26 | Southern Illinois (187) | 58 | 74 | Memphis (29) | Final | L | -16 |
| 8 | 2025-11-29 | Little Rock (231) | 65 | 74 | Southern Illinois (187) | Final | W | 9 |
| 9 | 2025-12-03 | Southern Illinois (231) | 86 | 84 | High Point (46) | Final | W | 2 |
| 10 | 2025-12-10 | Tennessee-Martin (132) | 54 | 83 | Southern Illinois (189) | Final | W | 29 |
| 11 | 2025-12-13 | Southern Illinois (189) | 84 | 93 | Richmond (67) | Final/OT | L | -9 |
| 12 | 2025-12-18 | Illinois State (89) | 75 | 68 | Southern Illinois (172) | Final | L | -7 |
| 13 | 2025-12-21 | Southern Illinois (185) | 69 | 73 | Bradley (114) | Final | L | -4 |
| 14 | 2025-12-29 | Southern Illinois (186) | 81 | 84 | Murray State (77) | Final | L | -3 |
| 15 | 2026-01-01 | Valparaiso (235) | 70 | 75 | Southern Illinois (186) | Final | W | 5 |
| 16 | 2026-01-04 | Southern Illinois (153) | 68 | 67 | Belmont (77) | Final | W | 1 |
| 17 | 2026-01-07 | Southern Illinois (153) | 57 | 70 | Illinois-Chicago (307) | Final | L | -13 |
| 18 | 2026-01-14 | Drake | Southern Illinois | Scheduled – 7:00 PM | – | – | ||
| 19 | 2026-01-17 | Belmont | Southern Illinois | Scheduled – 6:00 PM | – | – | ||
| 20 | 2026-01-21 | Southern Illinois | Valparaiso | Scheduled – 7:00 PM | – | – | ||
| 21 | 2026-01-25 | Southern Illinois | Evansville | Scheduled – 3:00 PM | – | – | ||
| 22 | 2026-01-28 | Northern Iowa | Southern Illinois | Scheduled – 6:00 PM | – | – | ||
| 23 | 2026-01-31 | Illinois-Chicago | Southern Illinois | Scheduled – 6:00 PM | – | – | ||
| 24 | 2026-02-03 | Southern Illinois | Illinois State | Scheduled – 6:00 PM | – | – | ||
| 25 | 2026-02-06 | Murray State | Southern Illinois | Scheduled – 7:00 PM | – | – | ||
| 26 | 2026-02-09 | Southern Illinois | Indiana State | Scheduled – 7:00 PM | – | – | ||
| 27 | 2026-02-12 | Evansville | Southern Illinois | Scheduled – 7:00 PM | – | – | ||
| 28 | 2026-02-15 | Bradley | Southern Illinois | Scheduled – 2:00 PM | – | – | ||
| 29 | 2026-02-18 | Southern Illinois | Drake | Scheduled – 6:00 PM | – | – | ||
| 30 | 2026-02-21 | Southern Illinois | Northern Iowa | Scheduled – 7:00 PM | – | – | ||
| 31 | 2026-02-25 | Indiana State | Southern Illinois | Scheduled – 7:00 PM | – | – |