Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Tennessee-Martin (237) | 58 | 80 | Pittsburgh (46) | Final | W | 22 |
| 2 | 2022-11-11 | West Virginia (42) | 81 | 56 | Pittsburgh (46) | Final | L | -25 |
| 3 | 2022-11-16 | Michigan (55) | 91 | 60 | Pittsburgh (46) | Final | L | -31 |
| 4 | 2022-11-17 | Pittsburgh (46) | 67 | 71 | Virginia Commonwealth (57) | Final | L | -4 |
| 5 | 2022-11-20 | Alabama State (352) | 54 | 73 | Pittsburgh (46) | Final | W | 19 |
| 6 | 2022-11-22 | Fairleigh Dickinson (286) | 61 | 83 | Pittsburgh (46) | Final | W | 22 |
| 7 | 2022-11-25 | William & Mary (289) | 64 | 80 | Pittsburgh (46) | Final | W | 16 |
| 8 | 2022-11-28 | Pittsburgh (46) | 87 | 58 | Northwestern (24) | Final | W | 29 |
| 9 | 2022-12-02 | Pittsburgh (46) | 68 | 60 | North Carolina State (26) | Final | W | 8 |
| 10 | 2022-12-07 | Pittsburgh (46) | 74 | 75 | Vanderbilt (70) | Final | L | -1 |
| 11 | 2022-12-10 | Sacred Heart (311) | 66 | 91 | Pittsburgh (46) | Final | W | 25 |
| 12 | 2022-12-17 | North Florida (247) | 56 | 82 | Pittsburgh (46) | Final | W | 26 |
| 13 | 2022-12-20 | Pittsburgh (46) | 84 | 82 | Syracuse (87) | Final | W | 2 |
| 14 | 2022-12-30 | North Carolina (47) | 74 | 76 | Pittsburgh (46) | Final | W | 2 |
| 15 | 2023-01-03 | Virginia (11) | 65 | 68 | Pittsburgh (46) | Final | W | 3 |
| 16 | 2023-01-07 | Clemson (63) | 75 | 74 | Pittsburgh (46) | Final | L | -1 |
| 17 | 2023-01-11 | Pittsburgh (46) | 69 | 77 | Duke (25) | Final | L | -8 |
| 18 | 2023-01-14 | Pittsburgh (46) | 71 | 60 | Georgia Tech (168) | Final | W | 11 |
| 19 | 2023-01-18 | Pittsburgh (46) | 75 | 54 | Louisville (287) | Final | W | 21 |
| 20 | 2023-01-21 | Florida State (209) | 71 | 64 | Pittsburgh (46) | Final | L | -7 |
| 21 | 2023-01-25 | Wake Forest (59) | 79 | 81 | Pittsburgh (46) | Final | W | 2 |
| 22 | 2023-01-28 | Miami (16) | 68 | 71 | Pittsburgh (46) | Final | W | 3 |
| 23 | 2023-02-01 | Pittsburgh (46) | 65 | 64 | North Carolina (47) | Final | W | 1 |
| 24 | 2023-02-07 | Louisville (287) | 57 | 91 | Pittsburgh (46) | Final | W | 34 |
| 25 | 2023-02-11 | Pittsburgh (108) | 83 | 75 | Florida State (64) | Final | W | 8 |
| 26 | 2023-02-14 | Boston College (142) | 58 | 77 | Pittsburgh (46) | Final | W | 19 |
| 27 | 2023-02-18 | Pittsburgh (108) | 72 | 79 | Virginia Tech (56) | Final | L | -7 |
| 28 | 2023-02-21 | Georgia Tech (168) | 68 | 76 | Pittsburgh (46) | Final | W | 8 |
| 29 | 2023-02-25 | Syracuse (97) | 82 | 99 | Pittsburgh (43) | Final | W | 17 |
| 30 | 2023-03-01 | Pittsburgh (108) | 81 | 88 | Notre Dame (101) | Final | L | -7 |
| 31 | 2023-03-04 | Pittsburgh (108) | 76 | 78 | Miami (27) | Final | L | -2 |
| 32 | 2023-03-08 | Georgia Tech (147) | 81 | 89 | Pittsburgh (48) | Final | W | 8 |
| 33 | 2023-03-09 | Pittsburgh (54) | 69 | 96 | Duke (17) | Final | L | -27 |
| 34 | 2023-03-14 | Pittsburgh | 60 | 59 | Mississippi State | Final | W | 1 |
| 35 | 2023-03-17 | Pittsburgh | 59 | 41 | Iowa State | Final | W | 18 |
| 36 | 2023-03-19 | Pittsburgh (52) | 73 | 84 | Xavier (18) | Final | L | -11 |