Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Jacksonville (233) | 44 | 71 | Duke (25) | Final | W | 27 |
| 2 | 2022-11-11 | South Carolina Upstate (253) | 38 | 84 | Duke (25) | Final | W | 46 |
| 3 | 2022-11-15 | Duke (25) | 64 | 69 | Kansas (3) | Final | L | -5 |
| 4 | 2022-11-18 | Delaware (220) | 58 | 92 | Duke (25) | Final | W | 34 |
| 5 | 2022-11-21 | Bellarmine (231) | 57 | 74 | Duke (25) | Final | W | 17 |
| 6 | 2022-11-24 | Duke (25) | 54 | 51 | Oregon State (204) | Final | W | 3 |
| 7 | 2022-11-25 | Duke (25) | 71 | 64 | Xavier (18) | Final | W | 7 |
| 8 | 2022-11-27 | Duke (25) | 56 | 75 | Purdue (4) | Final | L | -19 |
| 9 | 2022-11-30 | Ohio State (92) | 72 | 81 | Duke (25) | Final | W | 9 |
| 10 | 2022-12-03 | Boston College (142) | 59 | 75 | Duke (25) | Final | W | 16 |
| 11 | 2022-12-06 | Iowa (43) | 62 | 74 | Duke (25) | Final | W | 12 |
| 12 | 2022-12-10 | Maryland-Eastern Shore (208) | 55 | 82 | Duke (25) | Final | W | 27 |
| 13 | 2022-12-20 | Duke (25) | 70 | 81 | Wake Forest (59) | Final | L | -11 |
| 14 | 2022-12-31 | Florida State (209) | 67 | 86 | Duke (25) | Final | W | 19 |
| 15 | 2023-01-04 | Duke (25) | 60 | 84 | North Carolina State (26) | Final | L | -24 |
| 16 | 2023-01-07 | Duke (25) | 65 | 64 | Boston College (142) | Final | W | 1 |
| 17 | 2023-01-11 | Pittsburgh (46) | 69 | 77 | Duke (25) | Final | W | 8 |
| 18 | 2023-01-14 | Duke (25) | 64 | 72 | Clemson (63) | Final | L | -8 |
| 19 | 2023-01-21 | Miami (16) | 66 | 68 | Duke (25) | Final | W | 2 |
| 20 | 2023-01-23 | Duke (25) | 75 | 78 | Virginia Tech (66) | Final | L | -3 |
| 21 | 2023-01-28 | Duke (25) | 86 | 43 | Georgia Tech (168) | Final | W | 43 |
| 22 | 2023-01-31 | Wake Forest (59) | 73 | 75 | Duke (25) | Final | W | 2 |
| 23 | 2023-02-04 | North Carolina (47) | 57 | 63 | Duke (25) | Final | W | 6 |
| 24 | 2023-02-06 | Duke (25) | 59 | 81 | Miami (16) | Final | L | -22 |
| 25 | 2023-02-11 | Duke (25) | 62 | 69 | Virginia (11) | Final | L | -7 |
| 26 | 2023-02-14 | Notre Dame (199) | 64 | 68 | Duke (25) | Final | W | 4 |
| 27 | 2023-02-18 | Duke (25) | 77 | 55 | Syracuse (87) | Final | W | 22 |
| 28 | 2023-02-20 | Louisville (287) | 62 | 79 | Duke (25) | Final | W | 17 |
| 29 | 2023-02-25 | Virginia Tech (69) | 65 | 81 | Duke (22) | Final | W | 16 |
| 30 | 2023-02-28 | North Carolina State (35) | 67 | 71 | Duke (18) | Final | W | 4 |
| 31 | 2023-03-04 | Duke (18) | 62 | 57 | North Carolina (43) | Final | W | 5 |
| 32 | 2023-03-09 | Pittsburgh (54) | 69 | 96 | Duke (17) | Final | W | 27 |
| 33 | 2023-03-10 | Duke (17) | 85 | 78 | Miami (19) | Final | W | 7 |
| 34 | 2023-03-11 | Duke (14) | 59 | 49 | Virginia (17) | Final | W | 10 |
| 35 | 2023-03-16 | Oral Roberts | 51 | 74 | Duke | Final | W | 23 |
| 36 | 2023-03-18 | Duke (14) | 52 | 65 | Tennessee (11) | Final | L | -13 |