Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Maryland-Eastern Shore (208) | 65 | 84 | Old Dominion (141) | Final | L | -19 |
| 2 | 2022-11-12 | Bryn Athyn | 43 | 90 | Maryland-Eastern Shore (208) | Final | W | 47 |
| 3 | 2022-11-14 | Maryland-Eastern Shore (353) | 47 | 80 | Charlotte (173) | Final | L | -33 |
| 4 | 2022-11-18 | Maryland-Eastern Shore (208) | 64 | 69 | George Washington (191) | Final | L | -5 |
| 5 | 2022-11-22 | Marist (309) | 59 | 70 | Maryland-Eastern Shore (208) | Final | W | 11 |
| 6 | 2022-11-25 | Maryland-Eastern Shore (208) | 45 | 72 | Virginia (11) | Final | L | -27 |
| 7 | 2022-11-30 | Lehigh (276) | 60 | 64 | Maryland-Eastern Shore (353) | Final | W | 4 |
| 8 | 2022-12-02 | Maryland-Eastern Shore (208) | 59 | 79 | Liberty (68) | Final | L | -20 |
| 9 | 2022-12-06 | Maryland-Eastern Shore (353) | 54 | 67 | George Mason (86) | Final | L | -13 |
| 10 | 2022-12-10 | Maryland-Eastern Shore (208) | 55 | 82 | Duke (25) | Final | L | -27 |
| 11 | 2022-12-17 | Summit | 55 | 95 | Maryland-Eastern Shore (208) | Final | W | 40 |
| 12 | 2022-12-20 | Maryland-Eastern Shore (208) | 86 | 78 | Temple (108) | Final | W | 8 |
| 13 | 2022-12-28 | Maryland-Eastern Shore (353) | 74 | 67 | Columbia (193) | Final/OT | W | 7 |
| 14 | 2023-01-02 | St. Mary's (MD) | 56 | 87 | Maryland-Eastern Shore (208) | Final | W | 31 |
| 15 | 2023-01-07 | Maryland-Eastern Shore (208) | 46 | 57 | Norfolk State (143) | Final | L | -11 |
| 16 | 2023-01-09 | Howard (207) | 73 | 82 | Maryland-Eastern Shore (208) | Final | W | 9 |
| 17 | 2023-01-14 | Delaware State (356) | 66 | 68 | Maryland-Eastern Shore (208) | Final | W | 2 |
| 18 | 2023-01-21 | Maryland-Eastern Shore (208) | 76 | 70 | South Carolina State (350) | Final | W | 6 |
| 19 | 2023-01-23 | Maryland-Eastern Shore (208) | 59 | 58 | North Carolina Central (219) | Final | W | 1 |
| 20 | 2023-01-28 | Coppin State (346) | 75 | 94 | Maryland-Eastern Shore (208) | Final | W | 19 |
| 21 | 2023-01-30 | Maryland-Eastern Shore (208) | 72 | 58 | Morgan State (291) | Final | W | 14 |
| 22 | 2023-02-02 | Regent | 41 | 89 | Maryland-Eastern Shore (208) | Final | W | 48 |
| 23 | 2023-02-11 | Norfolk State (322) | 76 | 73 | Maryland-Eastern Shore (353) | Final | L | -3 |
| 24 | 2023-02-13 | Maryland-Eastern Shore (208) | 69 | 78 | Howard (207) | Final | L | -9 |
| 25 | 2023-02-18 | South Carolina State (355) | 62 | 78 | Maryland-Eastern Shore (353) | Final | W | 16 |
| 26 | 2023-02-20 | North Carolina Central (219) | 68 | 63 | Maryland-Eastern Shore (208) | Final | L | -5 |
| 27 | 2023-02-25 | Maryland-Eastern Shore (207) | 78 | 57 | Coppin State (329) | Final | W | 21 |
| 28 | 2023-02-27 | Morgan State (249) | 68 | 61 | Maryland-Eastern Shore (215) | Final | L | -7 |
| 29 | 2023-03-02 | Maryland-Eastern Shore (353) | 64 | 58 | Delaware State (361) | Final | W | 6 |
| 30 | 2023-03-09 | Morgan State (266) | 64 | 80 | Maryland-Eastern Shore (211) | Final | W | 16 |
| 31 | 2023-03-10 | Maryland-Eastern Shore (211) | 55 | 74 | Howard (204) | Final | L | -19 |