Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-09 | IUPUI (362) | 48 | 80 | Drake (64) | Final | W | 32 |
| 2 | 2022-11-14 | Wofford (221) | 72 | 80 | Drake (217) | Final | W | 8 |
| 3 | 2022-11-18 | Buffalo (202) | 72 | 80 | Drake (64) | Final | W | 8 |
| 4 | 2022-11-20 | Drake (64) | 61 | 56 | Wyoming (203) | Final | W | 5 |
| 5 | 2022-11-21 | Drake (64) | 71 | 64 | Tarleton State (161) | Final | W | 7 |
| 6 | 2022-11-26 | Louisiana (98) | 64 | 76 | Drake (64) | Final | W | 12 |
| 7 | 2022-11-30 | Drake (217) | 73 | 75 | Indiana State (243) | Final | L | -2 |
| 8 | 2022-12-03 | Illinois-Chicago (139) | 64 | 77 | Drake (217) | Final | W | 13 |
| 9 | 2022-12-07 | Nebraska-Omaha (313) | 65 | 78 | Drake (64) | Final | W | 13 |
| 10 | 2022-12-10 | Drake (64) | 52 | 82 | Richmond (157) | Final | L | -30 |
| 11 | 2022-12-17 | Drake (64) | 75 | 83 | Saint Louis (80) | Final | L | -8 |
| 12 | 2022-12-20 | Mississippi State (45) | 52 | 58 | Drake (64) | Final | W | 6 |
| 13 | 2022-12-21 | St. Ambrose | 48 | 124 | Drake (217) | Final | W | 76 |
| 14 | 2022-12-29 | Valparaiso (156) | 63 | 68 | Drake (217) | Final | W | 5 |
| 15 | 2023-01-01 | Drake (64) | 49 | 52 | Missouri State (160) | Final | L | -3 |
| 16 | 2023-01-04 | Drake (64) | 49 | 53 | Southern Illinois (113) | Final | L | -4 |
| 17 | 2023-01-07 | Murray State (179) | 64 | 82 | Drake (64) | Final | W | 18 |
| 18 | 2023-01-10 | Drake (64) | 76 | 71 | Illinois-Chicago (271) | Final | W | 5 |
| 19 | 2023-01-14 | Bradley (79) | 61 | 86 | Drake (64) | Final | W | 25 |
| 20 | 2023-01-18 | Missouri State (160) | 65 | 62 | Drake (64) | Final | L | -3 |
| 21 | 2023-01-21 | Drake (64) | 97 | 61 | Evansville (344) | Final | W | 36 |
| 22 | 2023-01-24 | Indiana State (114) | 68 | 70 | Drake (64) | Final | W | 2 |
| 23 | 2023-01-29 | Drake (64) | 79 | 61 | Belmont (121) | Final | W | 18 |
| 24 | 2023-02-01 | Northern Iowa (200) | 81 | 88 | Drake (64) | Final | W | 7 |
| 25 | 2023-02-04 | Drake (64) | 85 | 82 | Valparaiso (268) | Final | W | 3 |
| 26 | 2023-02-07 | Drake (64) | 92 | 68 | Murray State (179) | Final | W | 24 |
| 27 | 2023-02-11 | Southern Illinois (150) | 59 | 82 | Drake (217) | Final | W | 23 |
| 28 | 2023-02-15 | Drake (217) | 82 | 74 | Northern Iowa (89) | Final | W | 8 |
| 29 | 2023-02-19 | Belmont (121) | 56 | 70 | Drake (64) | Final | W | 14 |
| 30 | 2023-02-22 | Illinois State (94) | 51 | 82 | Drake (217) | Final | W | 31 |
| 31 | 2023-02-26 | Drake (66) | 61 | 73 | Bradley (70) | Final | L | -12 |
| 32 | 2023-03-03 | Murray State (116) | 62 | 74 | Drake (217) | Final | W | 12 |
| 33 | 2023-03-04 | Southern Illinois (150) | 52 | 65 | Drake (217) | Final | W | 13 |
| 34 | 2023-03-05 | Drake (55) | 77 | 51 | Bradley (73) | Final | W | 26 |
| 35 | 2023-03-17 | Drake | 56 | 63 | Miami | Final | L | -7 |