Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Colgate (124) | 87 | 88 | Buffalo (202) | Final | W | 1 |
| 2 | 2022-11-12 | James Madison (99) | 97 | 62 | Buffalo (202) | Final | L | -35 |
| 3 | 2022-11-15 | Buffalo (202) | 64 | 84 | Connecticut (13) | Final | L | -20 |
| 4 | 2022-11-18 | Buffalo (202) | 72 | 80 | Drake (64) | Final | L | -8 |
| 5 | 2022-11-19 | Buffalo (202) | 59 | 63 | Howard (207) | Final | L | -4 |
| 6 | 2022-11-21 | Buffalo (202) | 82 | 74 | George Mason (131) | Final | W | 8 |
| 7 | 2022-11-27 | Canisius (308) | 66 | 86 | Buffalo (202) | Final | W | 20 |
| 8 | 2022-12-03 | St. Bonaventure (171) | 66 | 83 | Buffalo (202) | Final | W | 17 |
| 9 | 2022-12-06 | St. John Fisher | 53 | 91 | Buffalo (202) | Final | W | 38 |
| 10 | 2022-12-10 | Tulane (72) | 88 | 63 | Buffalo (202) | Final | L | -25 |
| 11 | 2022-12-21 | SUNY-Canton | 62 | 129 | Buffalo (202) | Final | W | 67 |
| 12 | 2022-12-30 | Buffalo (202) | 68 | 89 | Michigan State (41) | Final | L | -21 |
| 13 | 2023-01-03 | Ohio (151) | 72 | 75 | Buffalo (202) | Final | W | 3 |
| 14 | 2023-01-07 | Northern Illinois (284) | 62 | 80 | Buffalo (202) | Final | W | 18 |
| 15 | 2023-01-10 | Buffalo (202) | 80 | 91 | Miami (OH) (317) | Final | L | -11 |
| 16 | 2023-01-14 | Buffalo (202) | 78 | 87 | Central Michigan (312) | Final | L | -9 |
| 17 | 2023-01-17 | Bowling Green (290) | 71 | 100 | Buffalo (202) | Final | W | 29 |
| 18 | 2023-01-20 | Toledo (100) | 86 | 77 | Buffalo (202) | Final | L | -9 |
| 19 | 2023-01-24 | Buffalo (202) | 91 | 65 | Ball State (145) | Final | W | 26 |
| 20 | 2023-01-27 | Buffalo (202) | 68 | 74 | Kent State (67) | Final | L | -6 |
| 21 | 2023-01-31 | Akron (106) | 81 | 64 | Buffalo (202) | Final | L | -17 |
| 22 | 2023-02-04 | Buffalo (202) | 85 | 76 | Western Michigan (338) | Final | W | 9 |
| 23 | 2023-02-07 | Eastern Michigan (335) | 97 | 102 | Buffalo (202) | Final | W | 5 |
| 24 | 2023-02-10 | Kent State (67) | 72 | 65 | Buffalo (202) | Final | L | -7 |
| 25 | 2023-02-14 | Buffalo (202) | 61 | 85 | Ohio (151) | Final | L | -24 |
| 26 | 2023-02-18 | Buffalo (202) | 66 | 86 | Akron (106) | Final | L | -20 |
| 27 | 2023-02-21 | Central Michigan (312) | 35 | 63 | Buffalo (202) | Final | W | 28 |
| 28 | 2023-02-25 | Buffalo (200) | 71 | 101 | Toledo (91) | Final | L | -30 |
| 29 | 2023-02-28 | Buffalo (195) | 85 | 75 | Northern Illinois (289) | Final | W | 10 |
| 30 | 2023-03-03 | Miami (OH) (284) | 63 | 68 | Buffalo (195) | Final | W | 5 |
| 31 | 2023-03-09 | Buffalo (196) | 77 | 101 | Akron (109) | Final | L | -24 |