Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-11-04 | Georgia Southern (235) | 89 | 92 | East Carolina (164) | Final | W | 3 |
| 2 | 2025-11-08 | East Carolina (164) | 72 | 87 | Richmond (257) | Final | L | -15 |
| 3 | 2025-11-13 | Elizabeth City State | 70 | 71 | East Carolina (164) | Final | W | 1 |
| 4 | 2025-11-18 | East Carolina (164) | 60 | 85 | UNC-Wilmington (95) | Final | L | -25 |
| 5 | 2025-11-21 | Charleston Southern (300) | 77 | 65 | East Carolina (164) | Final | L | -12 |
| 6 | 2025-11-25 | Michigan State (7) | 89 | 56 | East Carolina (164) | Final | L | -33 |
| 7 | 2025-11-27 | St. Bonaventure (107) | 67 | 58 | East Carolina (164) | Final | L | -9 |
| 8 | 2025-12-02 | Maryland-Eastern Shore | 56 | 68 | East Carolina (296) | Final | W | 12 |
| 9 | 2025-12-06 | UNC-Greensboro (330) | 82 | 78 | East Carolina (296) | Final | L | -4 |
| 10 | 2025-12-11 | Appalachian State (209) | 67 | 54 | East Carolina (294) | Final | L | -13 |
| 11 | 2025-12-14 | Buffalo (124) | 70 | 73 | East Carolina (265) | Final | W | 3 |
| 12 | 2025-12-17 | Presbyterian (235) | 53 | 74 | East Carolina (265) | Final | W | 21 |
| 13 | 2025-12-22 | East Carolina (249) | 51 | 99 | North Carolina (12) | Final | L | -48 |
| 14 | 2025-12-31 | Tulane (162) | 79 | 70 | East Carolina (253) | Final | L | -9 |
| 15 | 2026-01-07 | East Carolina (254) | 67 | 75 | Temple (145) | Final | L | -8 |
| 16 | 2026-01-11 | UAB (128) | 87 | 85 | East Carolina (276) | Final/OT | L | -2 |
| 17 | 2026-01-14 | East Carolina (276) | 71 | 82 | South Florida (81) | Final | L | -11 |
| 18 | 2026-01-18 | Charlotte (193) | 73 | 70 | East Carolina (291) | Final | L | -3 |
| 19 | 2026-01-21 | East Carolina (291) | 60 | 77 | Wichita State (121) | Final | L | -17 |
| 20 | 2026-01-23 | East Carolina (291) | 63 | 59 | North Texas (135) | Final | W | 4 |
| 21 | 2026-01-28 | Rice (240) | 83 | 77 | East Carolina (278) | Final | L | -6 |
| 22 | 2026-02-01 | East Carolina (272) | 76 | 75 | Florida Atlantic (107) | Final | W | 1 |
| 23 | 2026-02-07 | Temple (142) | 81 | 73 | East Carolina (272) | Final | L | -8 |
| 24 | 2026-02-11 | UTSA (346) | 72 | 88 | East Carolina (281) | Final | W | 16 |
| 25 | 2026-02-14 | East Carolina (281) | 85 | 75 | Rice (232) | Final | W | 10 |
| 26 | 2026-02-18 | Wichita State (97) | 92 | 89 | East Carolina (259) | Final/2OT | L | -3 |
| 27 | 2026-02-21 | East Carolina (259) | 56 | 68 | Charlotte (201) | Final | L | -12 |
| 28 | 2026-02-25 | East Carolina | UTSA | Scheduled – 7:00 PM | – | – | ||
| 29 | 2026-03-01 | Memphis | East Carolina | Scheduled – 2:00 PM | – | – | ||
| 30 | 2026-03-05 | Tulsa | East Carolina | Scheduled – 7:00 PM | – | – | ||
| 31 | 2026-03-08 | East Carolina | UAB | Scheduled – 2:00 PM | – | – |