Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Northwestern (90) | 3 | Tulane (36) | 23 | Final | W | 20 |
| 2 | 2025-09-06 | Tulane (36) | 33 | South Alabama (68) | 31 | Final | W | 2 |
| 3 | 2025-09-13 | Duke (44) | 27 | Tulane (36) | 34 | Final | W | 7 |
| 4 | 2025-09-20 | Tulane (41) | 10 | Ole Miss (2) | 45 | Final | L | -35 |
| 5 | 2025-09-27 | Tulane (29) | 31 | Tulsa (105) | 14 | Final | W | 17 |
| 6 | 2025-10-09 | East Carolina (64) | 19 | Tulane (21) | 26 | Final | W | 7 |
| 7 | 2025-10-18 | Army (97) | 17 | Tulane (24) | 24 | Final | W | 7 |
| 8 | 2025-10-30 | Tulane (38) | 26 | UTSA (69) | 48 | Final | L | -22 |
| 9 | 2025-11-07 | Tulane (32) | 38 | Memphis (36) | 32 | Final | W | 6 |
| 10 | 2025-11-15 | Florida Atlantic (106) | 24 | Tulane (27) | 35 | Final | W | 11 |
| 11 | 2025-11-22 | Tulane (23) | 37 | Temple (89) | 13 | Final | W | 24 |
| 12 | 2025-11-29 | Charlotte (154) | 0 | Tulane (27) | 27 | Final | W | 27 |