| 1 | 2025-11-03 | Mercyhurst | | | Northwestern | Scheduled – 7:00 PM | – | – |
| 2 | 2025-11-05 | Mercyhurst | | | Loyola-Chicago | Scheduled – 11:00 PM | – | – |
| 3 | 2025-11-08 | Penn State-New Kensington | | | Mercyhurst | Scheduled – 3:00 PM | – | – |
| 4 | 2025-11-12 | Mercyhurst | | | Canisius | Scheduled – 12:00 AM | – | – |
| 5 | 2025-11-15 | Morgan State | | | Mercyhurst | Scheduled – 4:00 PM | – | – |
| 6 | 2025-11-20 | Mercyhurst | | | Miami (OH) | Scheduled – 12:00 AM | – | – |
| 7 | 2025-11-23 | Mercyhurst | | | Marshall | Scheduled – 12:00 AM | – | – |
| 8 | 2025-11-30 | Mercyhurst | | | West Virginia | Scheduled – 12:00 AM | – | – |
| 9 | 2025-12-05 | Mercyhurst | | | Lafayette | Scheduled – 7:00 PM | – | – |
| 10 | 2025-12-07 | Bethany (WV) | | | Mercyhurst | Scheduled – 2:00 PM | – | – |
| 11 | 2025-12-13 | Mercyhurst | | | Davidson | Scheduled – 12:00 AM | – | – |
| 12 | 2025-12-17 | Mercyhurst | | | Syracuse | Scheduled – 12:00 AM | – | – |
| 13 | 2025-12-20 | Binghamton | | | Mercyhurst | Scheduled – 2:00 PM | – | – |
| 14 | 2026-01-02 | Fairleigh Dickinson | | | Mercyhurst | Scheduled – 7:30 PM | – | – |
| 15 | 2026-01-04 | Le Moyne | | | Mercyhurst | Scheduled – 12:00 AM | – | – |
| 16 | 2026-01-08 | Mercyhurst | | | Long Island | Scheduled – 12:00 AM | – | – |
| 17 | 2026-01-10 | Mercyhurst | | | Wagner | Scheduled – 12:00 AM | – | – |
| 18 | 2026-01-17 | Stonehill | | | Mercyhurst | Scheduled – 2:00 PM | – | – |
| 19 | 2026-01-19 | Central Connecticut State | | | Mercyhurst | Scheduled – 2:00 PM | – | – |
| 20 | 2026-01-23 | Mercyhurst | | | New Haven | Scheduled – 6:00 PM | – | – |
| 21 | 2026-01-25 | Chicago State | | | Mercyhurst | Scheduled – 2:00 PM | – | – |
| 22 | 2026-01-29 | New Haven | | | Mercyhurst | Scheduled – 7:00 PM | – | – |
| 23 | 2026-01-30 | Mercyhurst | | | Chicago State | Scheduled – 11:00 PM | – | – |
| 24 | 2026-02-05 | Saint Francis | | | Mercyhurst | Scheduled – 7:00 PM | – | – |
| 25 | 2026-02-07 | Mercyhurst | | | Fairleigh Dickinson | Scheduled – 3:30 PM | – | – |
| 26 | 2026-02-12 | Mercyhurst | | | Le Moyne | Scheduled – 7:00 PM | – | – |
| 27 | 2026-02-14 | Mercyhurst | | | Saint Francis | Scheduled – 12:00 AM | – | – |
| 28 | 2026-02-19 | Wagner | | | Mercyhurst | Scheduled – 7:00 PM | – | – |
| 29 | 2026-02-21 | Long Island | | | Mercyhurst | Scheduled – 2:00 PM | – | – |
| 30 | 2026-02-26 | Mercyhurst | | | Central Connecticut State | Scheduled – 7:00 PM | – | – |
| 31 | 2026-02-28 | Mercyhurst | | | Stonehill | Scheduled – 2:00 PM | – | – |
