NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Colorado State-Pueblo | 53 | 67 | Wyoming (121) | Final | W | 14 |
| 2 | 2021-11-13 | Wichita State (180) | 57 | 48 | Wyoming (121) | Final | L | -9 |
| 3 | 2021-11-18 | Wyoming (253) | 44 | 53 | UMKC (309) | Final | L | -9 |
| 4 | 2021-11-22 | Chadron State | 48 | 71 | Wyoming (281) | Final | W | 23 |
| 5 | 2021-11-26 | Wyoming (253) | 67 | 73 | Tulane (211) | Final | L | -6 |
| 6 | 2021-11-27 | Wyoming (289) | 81 | 51 | Denver (316) | Final | W | 30 |
| 7 | 2021-12-03 | Wyoming (214) | 47 | 54 | Gonzaga (36) | Final | L | -7 |
| 8 | 2021-12-12 | North Dakota State (185) | 45 | 71 | Wyoming (229) | Final | W | 26 |
| 9 | 2021-12-22 | Wyoming (179) | 61 | 72 | Nebraska (5) | Final | L | -11 |
| 10 | 2021-12-28 | Wyoming (253) | 62 | 54 | San Diego State (63) | Final | W | 8 |
| 11 | 2021-12-31 | Wyoming (253) | 60 | 66 | UNLV (97) | Final | L | -6 |
| 12 | 2022-01-03 | Boise State (285) | 0 | 0 | Wyoming (176) | Postponed | - | - |
| 13 | 2022-01-06 | Wyoming (175) | 0 | 0 | San Jose State (324) | Postponed | - | - |
| 14 | 2022-01-09 | Fresno State (208) | 0 | 0 | Wyoming (253) | Postponed | - | - |
| 15 | 2022-01-13 | New Mexico (113) | 85 | 76 | Wyoming (253) | Final | L | -9 |
| 16 | 2022-01-15 | Air Force (194) | 54 | 57 | Wyoming (179) | Final | W | 3 |
| 17 | 2022-01-19 | Wyoming (253) | 59 | 70 | Boise State (104) | Final | L | -11 |
| 18 | 2022-01-22 | Wyoming (171) | 66 | 76 | Utah State (279) | Final | L | -10 |
| 19 | 2022-01-26 | Boise State (247) | 47 | 61 | Wyoming (208) | Final | W | 14 |
| 20 | 2022-01-29 | Nevada (139) | 53 | 62 | Wyoming (208) | Final | W | 9 |
| 21 | 2022-02-02 | Wyoming (183) | 45 | 47 | Air Force (179) | Final | L | -2 |
| 22 | 2022-02-05 | Wyoming (253) | 60 | 59 | New Mexico (113) | Final | W | 1 |
| 23 | 2022-02-09 | San Jose State (333) | 54 | 75 | Wyoming (253) | Final | W | 21 |
| 24 | 2022-02-12 | Wyoming (177) | 61 | 58 | Fresno State (221) | Final | W | 3 |
| 25 | 2022-02-14 | Wyoming (177) | 84 | 64 | San Jose State (322) | Final | W | 20 |
| 26 | 2022-02-17 | Wyoming (169) | 45 | 56 | Colorado State (151) | Final | L | -11 |
| 27 | 2022-02-24 | UNLV (71) | 73 | 77 | Wyoming (179) | Final | W | 4 |
| 28 | 2022-02-26 | San Diego State (188) | 46 | 70 | Wyoming (179) | Final | W | 24 |
| 29 | 2022-03-02 | Colorado State (150) | 63 | 69 | Wyoming (155) | Final/OT | W | 6 |
| 30 | 2022-03-07 | Colorado State (150) | 51 | 38 | Wyoming (155) | Final | L | -13 |
| 31 | 2022-03-17 | Idaho State (161) | 73 | 76 | Wyoming (156) | Final/OT | W | 3 |
| 32 | 2022-03-20 | Tulsa (108) | 90 | 97 | Wyoming (156) | Final/3OT | W | 7 |
| 33 | 2022-03-24 | UCLA (65) | 82 | 81 | Wyoming (156) | Final/3OT | L | -1 |