NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Loyola Marymount (117) | 55 | 85 | USC (25) | Final | W | 30 |
| 2 | 2020-11-29 | UC-Riverside (295) | USC (54) | Cancelled | - | - | ||
| 3 | 2020-12-04 | USC (25) | 58 | 63 | Arizona State (46) | Final | L | -5 |
| 4 | 2020-12-06 | USC (25) | 77 | 78 | Arizona (123) | Final | L | -1 |
| 5 | 2020-12-13 | UCLA (1) | 73 | 52 | USC (25) | Final | L | -21 |
| 6 | 2020-12-19 | Stanford (56) | 80 | 60 | USC (25) | Final | L | -20 |
| 7 | 2020-12-21 | California (60) | 54 | 77 | USC (25) | Final | W | 23 |
| 8 | 2020-12-23 | Long Beach State (335) | 65 | 71 | USC (25) | Final | W | 6 |
| 9 | 2021-01-01 | USC (25) | 69 | 92 | Oregon (31) | Final | L | -23 |
| 10 | 2021-01-03 | USC (25) | 0 | 0 | Oregon State (100) | Cancelled | - | - |
| 11 | 2021-01-08 | Utah (61) | 59 | 60 | USC (25) | Final | W | 1 |
| 12 | 2021-01-11 | Colorado (155) | 52 | 56 | USC (99) | Final | W | 4 |
| 13 | 2021-01-15 | Washington State (244) | 77 | 81 | USC (25) | Final/OT | W | 4 |
| 14 | 2021-01-17 | Washington (124) | USC (78) | Cancelled | - | - | ||
| 15 | 2021-01-17 | UC-Riverside (267) | 54 | 52 | USC (25) | Final | L | -2 |
| 16 | 2021-01-22 | USC (25) | 0 | 0 | California (60) | Cancelled | - | - |
| 17 | 2021-01-24 | USC (25) | 59 | 86 | Stanford (56) | Final | L | -27 |
| 18 | 2021-01-29 | Arizona (123) | 0 | 0 | USC (25) | Postponed | - | - |
| 19 | 2021-01-31 | Arizona State (46) | 57 | 65 | USC (25) | Final | W | 8 |
| 20 | 2021-02-05 | USC (25) | 63 | 54 | Washington (23) | Final | W | 9 |
| 21 | 2021-02-07 | USC (25) | 81 | 71 | Washington State (244) | Final | W | 10 |
| 22 | 2021-02-12 | USC (25) | 56 | 66 | Colorado (40) | Final | L | -10 |
| 23 | 2021-02-14 | USC (25) | 66 | 49 | Utah (61) | Final | W | 17 |
| 24 | 2021-02-19 | Oregon State (100) | 77 | 52 | USC (25) | Final | L | -25 |
| 25 | 2021-02-21 | Oregon (31) | 72 | 48 | USC (25) | Final | L | -24 |
| 26 | 2021-02-26 | USC (25) | 51 | 93 | UCLA (1) | Final | L | -42 |
| 27 | 2021-03-03 | Arizona State (46) | 65 | 71 | USC (25) | Final | W | 6 |
| 28 | 2021-03-04 | USC (88) | 53 | 92 | Stanford (5) | Final | L | -39 |