NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-12-02 | Siena (295) | 0 | 0 | Albany (207) | Cancelled | - | - |
| 2 | 2020-12-05 | Fairleigh Dickinson (105) | 0 | 0 | Siena (295) | Cancelled | - | - |
| 3 | 2020-12-11 | Fairfield (137) | 68 | 56 | Siena (193) | Final | L | -12 |
| 4 | 2020-12-12 | Fairfield (50) | 76 | 44 | Siena (295) | Final | L | -32 |
| 5 | 2020-12-18 | Siena (295) | 0 | 0 | Canisius (347) | Cancelled | - | - |
| 6 | 2020-12-19 | Siena (295) | Canisius (311) | Postponed | - | - | ||
| 7 | 2020-12-23 | Siena (295) | 0 | 0 | Albany (207) | Cancelled | - | - |
| 8 | 2021-01-01 | Siena (295) | 0 | 0 | Monmouth (185) | Postponed | - | - |
| 9 | 2021-01-02 | Siena (295) | 0 | 0 | Monmouth (185) | Postponed | - | - |
| 10 | 2021-01-03 | Siena (295) | 0 | 0 | Canisius (347) | Cancelled | - | - |
| 11 | 2021-01-04 | Siena (295) | 0 | 0 | Canisius (347) | Cancelled | - | - |
| 12 | 2021-01-08 | Siena (287) | Rider (345) | Cancelled | - | - | ||
| 13 | 2021-01-08 | Siena (287) | Quinnipiac (124) | Cancelled | - | - | ||
| 14 | 2021-01-09 | Rider (339) | 64 | 73 | Siena (295) | Final | W | 9 |
| 15 | 2021-01-10 | Rider (339) | 60 | 69 | Siena (295) | Final | W | 9 |
| 16 | 2021-01-15 | Siena (295) | 0 | 0 | Quinnipiac (99) | Postponed | - | - |
| 17 | 2021-01-16 | Quinnipiac (99) | 0 | 0 | Siena (295) | Cancelled | - | - |
| 18 | 2021-01-22 | Siena (234) | Saint Peter's (283) | Cancelled | - | - | ||
| 19 | 2021-01-22 | Siena (234) | Monmouth (314) | Cancelled | - | - | ||
| 20 | 2021-01-23 | Siena (234) | Saint Peter's (283) | Cancelled | - | - | ||
| 21 | 2021-01-23 | Siena (234) | Monmouth (314) | Cancelled | - | - | ||
| 22 | 2021-01-29 | Niagara (258) | Siena (227) | Cancelled | - | - | ||
| 23 | 2021-01-30 | Niagara (258) | Siena (227) | Cancelled | - | - | ||
| 24 | 2021-01-30 | Siena (295) | 0 | 0 | Quinnipiac (99) | Postponed | - | - |
| 25 | 2021-01-31 | Siena (295) | 0 | 0 | Quinnipiac (99) | Postponed | - | - |
| 26 | 2021-02-03 | Niagara (254) | Siena (221) | Postponed | - | - | ||
| 27 | 2021-02-03 | Siena (295) | 60 | 61 | Monmouth (185) | Final | L | -1 |
| 28 | 2021-02-06 | Siena (221) | Monmouth (338) | Cancelled | - | - | ||
| 29 | 2021-02-06 | Siena (221) | Manhattan (210) | Cancelled | - | - | ||
| 30 | 2021-02-06 | Siena (221) | Quinnipiac (159) | Cancelled | - | - | ||
| 31 | 2021-02-07 | Siena (221) | Manhattan (210) | Cancelled | - | - | ||
| 32 | 2021-02-13 | Marist (300) | 69 | 44 | Siena (295) | Final | L | -25 |
| 33 | 2021-02-14 | Marist (300) | 60 | 44 | Siena (295) | Final | L | -16 |
| 34 | 2021-02-17 | Niagara (252) | Siena (263) | Cancelled | - | - | ||
| 35 | 2021-02-17 | Siena (295) | 63 | 84 | Quinnipiac (99) | Final | L | -21 |
| 36 | 2021-02-19 | Siena (263) | Quinnipiac (151) | Cancelled | - | - | ||
| 37 | 2021-02-20 | Siena (263) | Quinnipiac (151) | Cancelled | - | - | ||
| 38 | 2021-02-20 | Siena (263) | Canisius (331) | Cancelled | - | - | ||
| 39 | 2021-02-21 | Siena (263) | Canisius (331) | Cancelled | - | - | ||
| 40 | 2021-02-21 | Quinnipiac (151) | Siena (263) | Cancelled | - | - | ||
| 41 | 2021-02-21 | Siena (295) | 63 | 60 | Quinnipiac (99) | Final | W | 3 |
| 42 | 2021-02-24 | Siena (263) | Manhattan (200) | Cancelled | - | - | ||
| 43 | 2021-02-24 | Siena (295) | 0 | 0 | Monmouth (185) | Cancelled | - | - |
| 44 | 2021-02-26 | Siena (295) | 58 | 66 | Saint Peter's (340) | Final | L | -8 |
| 45 | 2021-02-27 | Iona (262) | Siena (263) | Cancelled | - | - | ||
| 46 | 2021-02-27 | Siena (295) | 54 | 62 | Saint Peter's (340) | Final | L | -8 |
| 47 | 2021-02-28 | Iona (262) | Siena (263) | Cancelled | - | - | ||
| 48 | 2021-03-04 | Canisius (331) | Siena (263) | Cancelled | - | - | ||
| 49 | 2021-03-04 | Niagara (258) | 0 | 0 | Siena (289) | Cancelled | - | - |
| 50 | 2021-03-05 | Marist (75) | Siena (263) | Cancelled | - | - | ||
| 51 | 2021-03-05 | Canisius (331) | Siena (263) | Cancelled | - | - | ||
| 52 | 2021-03-05 | Niagara (362) | 0 | 0 | Siena (295) | Cancelled | - | - |
| 53 | 2021-03-06 | Marist (300) | 0 | 0 | Siena (295) | Cancelled | - | - |
| 54 | 2021-03-09 | Siena (291) | 74 | 65 | Niagara (257) | Final | W | 9 |
| 55 | 2021-03-10 | Siena (291) | 55 | 63 | Marist (91) | Final | L | -8 |