NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-09 | American (123) | 45 | 96 | DePaul (45) | Final | W | 51 |
| 2 | 2022-11-12 | DePaul (45) | 79 | 86 | Northern Illinois (173) | Final | L | -7 |
| 3 | 2022-11-15 | Cleveland State (195) | 90 | 83 | DePaul (179) | Final/OT | L | -7 |
| 4 | 2022-11-20 | Miami (37) | 83 | 98 | DePaul (179) | Final | W | 15 |
| 5 | 2022-11-25 | DePaul (115) | 76 | 67 | Maryland (21) | Final | W | 9 |
| 6 | 2022-11-26 | Pittsburgh (279) | 59 | 74 | DePaul (229) | Final | W | 15 |
| 7 | 2022-11-27 | DePaul (115) | 56 | 64 | Towson (112) | Final | L | -8 |
| 8 | 2022-12-04 | DePaul (69) | 78 | 72 | Butler (162) | Final | W | 6 |
| 9 | 2022-12-07 | DePaul (71) | 78 | 52 | Loyola-Chicago (255) | Final | W | 26 |
| 10 | 2022-12-10 | DePaul (71) | 81 | 63 | Northwestern (110) | Final | W | 18 |
| 11 | 2022-12-12 | Howard (251) | 56 | 81 | DePaul (71) | Final | W | 25 |
| 12 | 2022-12-18 | Georgetown (108) | 71 | 80 | DePaul (56) | Final | W | 9 |
| 13 | 2022-12-21 | Louisville (13) | 81 | 67 | DePaul (229) | Final | L | -14 |
| 14 | 2022-12-28 | Providence (129) | 69 | 78 | DePaul (68) | Final | W | 9 |
| 15 | 2022-12-31 | Creighton (24) | 92 | 82 | DePaul (68) | Final | L | -10 |
| 16 | 2023-01-04 | Marquette (49) | 72 | 63 | DePaul (65) | Final | L | -9 |
| 17 | 2023-01-08 | DePaul (229) | 0 | 0 | Connecticut (2) | Postponed | - | - |
| 18 | 2023-01-11 | Villanova (26) | 71 | 64 | DePaul (72) | Final | L | -7 |
| 19 | 2023-01-14 | DePaul (72) | 91 | 56 | Xavier (178) | Final | W | 35 |
| 20 | 2023-01-18 | DePaul (72) | 73 | 87 | Georgetown (140) | Final | L | -14 |
| 21 | 2023-01-21 | St. John's (43) | 81 | 72 | DePaul (72) | Final | L | -9 |
| 22 | 2023-01-23 | DePaul (72) | 51 | 94 | Connecticut (4) | Final | L | -43 |
| 23 | 2023-01-28 | DePaul (81) | 0 | 0 | Seton Hall (59) | Postponed | - | - |
| 24 | 2023-02-01 | DePaul (229) | 74 | 83 | Creighton (98) | Final | L | -9 |
| 25 | 2023-02-04 | Xavier (196) | 48 | 93 | DePaul (81) | Final | W | 45 |
| 26 | 2023-02-08 | Butler (156) | 62 | 87 | DePaul (81) | Final | W | 25 |
| 27 | 2023-02-11 | DePaul (229) | 61 | 77 | St. John's (87) | Final | L | -16 |
| 28 | 2023-02-13 | DePaul (81) | 82 | 89 | Seton Hall (53) | Final | L | -7 |
| 29 | 2023-02-15 | Seton Hall (55) | 89 | 94 | DePaul (79) | Final | W | 5 |
| 30 | 2023-02-18 | DePaul (79) | 86 | 64 | Providence (120) | Final | W | 22 |
| 31 | 2023-02-21 | DePaul (73) | 64 | 67 | Villanova (14) | Final | L | -3 |
| 32 | 2023-02-25 | Connecticut (5) | 72 | 69 | DePaul (73) | Final | L | -3 |
| 33 | 2023-02-27 | DePaul (73) | 80 | 98 | Marquette (34) | Final | L | -18 |
| 34 | 2023-03-03 | Providence (138) | 54 | 67 | DePaul (73) | Final | W | 13 |
| 35 | 2023-03-04 | DePaul (73) | 70 | 71 | Villanova (13) | Final | L | -1 |