NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Columbia International | 52 | 79 | Charleston Southern (317) | Final | W | 27 |
| 2 | 2020-12-02 | Charleston Southern (317) | 52 | 67 | Florida (55) | Final | L | -15 |
| 3 | 2020-12-09 | Charleston Southern (244) | 56 | 85 | Davidson (310) | Final | L | -29 |
| 4 | 2020-12-13 | Western Carolina (353) | 56 | 66 | Charleston Southern (317) | Final | W | 10 |
| 5 | 2020-12-16 | Florida A&M (338) | 0 | 0 | Charleston Southern (317) | Cancelled | - | - |
| 6 | 2020-12-21 | Charleston Southern (317) | 49 | 47 | Hampton (305) | Final | W | 2 |
| 7 | 2020-12-22 | Charleston Southern (317) | 58 | 53 | Hampton (305) | Final | W | 5 |
| 8 | 2021-01-04 | Gardner-Webb (318) | Charleston Southern (219) | Cancelled | - | - | ||
| 9 | 2021-01-04 | Presbyterian (357) | 62 | 51 | Charleston Southern (317) | Final | L | -11 |
| 10 | 2021-01-05 | Gardner-Webb (318) | Charleston Southern (219) | Cancelled | - | - | ||
| 11 | 2021-01-05 | Presbyterian (357) | 63 | 66 | Charleston Southern (317) | Final | W | 3 |
| 12 | 2021-01-09 | Charleston Southern (253) | Radford (319) | Cancelled | - | - | ||
| 13 | 2021-01-09 | Gardner-Webb (303) | 75 | 62 | Charleston Southern (317) | Final | L | -13 |
| 14 | 2021-01-10 | Charleston Southern (253) | Radford (319) | Cancelled | - | - | ||
| 15 | 2021-01-10 | Gardner-Webb (303) | 68 | 59 | Charleston Southern (317) | Final | L | -9 |
| 16 | 2021-01-15 | UNC-Asheville (308) | 63 | 67 | Charleston Southern (317) | Final | W | 4 |
| 17 | 2021-01-16 | UNC-Asheville (308) | 65 | 58 | Charleston Southern (317) | Final | L | -7 |
| 18 | 2021-01-22 | Campbell (181) | 57 | 35 | Charleston Southern (317) | Final | L | -22 |
| 19 | 2021-01-23 | Campbell (181) | 66 | 51 | Charleston Southern (317) | Final | L | -15 |
| 20 | 2021-01-29 | Charleston Southern (317) | 56 | 59 | Winthrop (276) | Final | L | -3 |
| 21 | 2021-01-30 | Charleston Southern (317) | 48 | 53 | Winthrop (276) | Final | L | -5 |
| 22 | 2021-02-05 | High Point (103) | 88 | 65 | Charleston Southern (317) | Final | L | -23 |
| 23 | 2021-02-06 | High Point (103) | 71 | 54 | Charleston Southern (317) | Final | L | -17 |
| 24 | 2021-02-12 | Charleston Southern (317) | 48 | 94 | Longwood (171) | Final | L | -46 |
| 25 | 2021-02-13 | Charleston Southern (317) | 51 | 76 | Longwood (171) | Final | L | -25 |
| 26 | 2021-02-19 | Presbyterian (245) | Charleston Southern (310) | Cancelled | - | - | ||
| 27 | 2021-02-20 | Presbyterian (245) | Charleston Southern (310) | Cancelled | - | - | ||
| 28 | 2021-02-20 | Charleston Southern (317) | 73 | 74 | Radford (174) | Final | L | -1 |
| 29 | 2021-02-21 | Charleston Southern (317) | 67 | 76 | Radford (174) | Final/OT | L | -9 |
| 30 | 2021-02-25 | Charleston Southern (317) | 0 | 0 | South Carolina Upstate (315) | Cancelled | - | - |
| 31 | 2021-02-26 | Charleston Southern (317) | 0 | 0 | South Carolina Upstate (315) | Cancelled | - | - |
| 32 | 2021-03-06 | Charleston Southern | UNC-Asheville | Cancelled | - | - | ||
| 33 | 2021-03-06 | Charleston Southern (317) | 64 | 72 | South Carolina Upstate (315) | Final | L | -8 |