NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2024-11-06 | Mercyhurst (313) | 53 | 74 | DePaul (229) | Final | W | 21 |
| 2 | 2024-11-09 | Princeton (274) | 79 | 58 | DePaul (123) | Final | L | -21 |
| 3 | 2024-11-12 | DePaul (231) | 75 | 60 | Loyola-Chicago (117) | Final | W | 15 |
| 4 | 2024-11-17 | Texas (50) | 91 | 61 | DePaul (145) | Final | L | -30 |
| 5 | 2024-11-21 | DePaul (161) | 57 | 70 | Green Bay (173) | Final | L | -13 |
| 6 | 2024-11-25 | DePaul (201) | 62 | 85 | Oklahoma (4) | Final | L | -23 |
| 7 | 2024-11-27 | DePaul (208) | 66 | 92 | Kansas State (26) | Final | L | -26 |
| 8 | 2024-12-01 | SIU-Edwardsville (356) | 42 | 66 | DePaul (206) | Final | W | 24 |
| 9 | 2024-12-04 | DePaul (184) | 56 | 64 | Northwestern (125) | Final | L | -8 |
| 10 | 2024-12-08 | DePaul (184) | 61 | 89 | Michigan State (1) | Final | L | -28 |
| 11 | 2024-12-13 | Illinois-Chicago (226) | 56 | 73 | DePaul (208) | Final | W | 17 |
| 12 | 2024-12-15 | UNLV (55) | 80 | 61 | DePaul (208) | Final | L | -19 |
| 13 | 2024-12-17 | Southern (285) | 64 | 76 | DePaul (184) | Final | W | 12 |
| 14 | 2024-12-21 | Butler (57) | 43 | 66 | DePaul (184) | Final | W | 23 |
| 15 | 2024-12-29 | Marquette (83) | 78 | 59 | DePaul (229) | Final | L | -19 |
| 16 | 2025-01-02 | DePaul (146) | 65 | 60 | Xavier (248) | Final | W | 5 |
| 17 | 2025-01-07 | DePaul (147) | 67 | 60 | St. John's (75) | Final | W | 7 |
| 18 | 2025-01-12 | Providence (140) | 56 | 62 | DePaul (147) | Final | W | 6 |
| 19 | 2025-01-15 | DePaul (229) | 55 | 66 | Villanova (35) | Final | L | -11 |
| 20 | 2025-01-18 | DePaul (229) | 71 | 92 | Creighton (98) | Final | L | -21 |
| 21 | 2025-01-22 | Xavier (190) | 50 | 57 | DePaul (229) | Final | W | 7 |
| 22 | 2025-01-26 | DePaul (130) | 74 | 67 | Butler (104) | Final/OT | W | 7 |
| 23 | 2025-01-29 | Connecticut (2) | 84 | 58 | DePaul (229) | Final | L | -26 |
| 24 | 2025-02-01 | Seton Hall (70) | 72 | 55 | DePaul (229) | Final | L | -17 |
| 25 | 2025-02-06 | DePaul (123) | 63 | 76 | Providence (163) | Final | L | -13 |
| 26 | 2025-02-09 | DePaul (229) | 80 | 76 | Georgetown (119) | Final | W | 4 |
| 27 | 2025-02-12 | Villanova (35) | 62 | 56 | DePaul (229) | Final | L | -6 |
| 28 | 2025-02-15 | DePaul (229) | 72 | 82 | Marquette (83) | Final | L | -10 |
| 29 | 2025-02-23 | Creighton (24) | 83 | 74 | DePaul (126) | Final | L | -9 |
| 30 | 2025-02-27 | DePaul (122) | 67 | 76 | Seton Hall (50) | Final | L | -9 |
| 31 | 2025-03-02 | St. John's (98) | 64 | 65 | DePaul (122) | Final/OT | W | 1 |
| 32 | 2025-03-07 | Xavier (258) | 80 | 73 | DePaul (120) | Final | L | -7 |