Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2019-08-31 | Georgia (5) | 30 | Vanderbilt (52) | 6 | Final | L | -24 |
| 2 | 2019-09-07 | Vanderbilt (52) | 24 | Purdue (50) | 42 | Final | L | -18 |
| 3 | 2019-09-21 | LSU (8) | 66 | Vanderbilt (52) | 38 | Final | L | -28 |
| 4 | 2019-09-28 | Northern Illinois (109) | 18 | Vanderbilt (118) | 24 | Final | W | 6 |
| 5 | 2019-10-05 | Vanderbilt (102) | 6 | Ole Miss (82) | 31 | Final | L | -25 |
| 6 | 2019-10-12 | UNLV (121) | 34 | Vanderbilt (113) | 10 | Final | L | -24 |
| 7 | 2019-10-19 | Missouri (21) | 14 | Vanderbilt (120) | 21 | Final | W | 7 |
| 8 | 2019-11-02 | Vanderbilt (110) | 7 | South Carolina (64) | 24 | Final | L | -17 |
| 9 | 2019-11-09 | Vanderbilt (113) | 0 | Florida (17) | 56 | Final | L | -56 |
| 10 | 2019-11-16 | Kentucky (63) | 38 | Vanderbilt (117) | 14 | Final | L | -24 |
| 11 | 2019-11-23 | East Tennessee State (225) | 0 | Vanderbilt (120) | 38 | Final | W | 38 |
| 12 | 2019-11-30 | Vanderbilt (116) | 10 | Tennessee (40) | 28 | Final | L | -18 |