Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-09-05 | Arkansas State (85) | 6 | USC (28) | 55 | Final | W | 49 |
| 2 | 2015-09-12 | Idaho (126) | 9 | USC (28) | 59 | Final | W | 50 |
| 3 | 2015-09-19 | Stanford (65) | 41 | USC (5) | 31 | Final | L | -10 |
| 4 | 2015-09-26 | USC (35) | 42 | Arizona State (60) | 14 | Final | W | 28 |
| 5 | 2015-10-08 | Washington (59) | 17 | USC (25) | 12 | Final | L | -5 |
| 6 | 2015-10-17 | USC (35) | 31 | Notre Dame (18) | 41 | Final | L | -10 |
| 7 | 2015-10-24 | Utah (1) | 24 | USC (39) | 42 | Final | W | 18 |
| 8 | 2015-10-31 | USC | 27 | California | 21 | Final | W | 6 |
| 9 | 2015-11-07 | Arizona (65) | 30 | USC (21) | 38 | Final | W | 8 |
| 10 | 2015-11-13 | USC (22) | 27 | Colorado (92) | 24 | Final | W | 3 |
| 11 | 2015-11-21 | USC (22) | 28 | Oregon (38) | 48 | Final | L | -20 |
| 12 | 2015-11-28 | UCLA (34) | 21 | USC (30) | 40 | Final | W | 19 |
| 13 | 2015-12-05 | USC (27) | 22 | Stanford (10) | 41 | Final | L | -19 |
| 14 | 2015-12-30 | USC (29) | 21 | Wisconsin (23) | 23 | Final | L | -2 |