Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-09-05 | Prairie View A&M | 38 | Texas Southern | 11 | Final | L | -27 |
| 2 | 2015-09-11 | Bacone College | 0 | Texas Southern | 63 | Final | W | 63 |
| 3 | 2015-09-19 | Texas Southern | 24 | Arkansas-Pine Bluff | 20 | Final | W | 4 |
| 4 | 2015-09-26 | Texas Southern | 30 | Jackson State | 34 | Final | L | -4 |
| 5 | 2015-10-01 | Alabama State | 41 | Texas Southern | 23 | Final | L | -18 |
| 6 | 2015-10-17 | Texas Southern | 49 | Mississippi Valley State | 21 | Final | W | 28 |
| 7 | 2015-10-24 | Southern | 40 | Texas Southern | 21 | Final | L | -19 |
| 8 | 2015-10-31 | Faith-Arkansas | 0 | Texas Southern | 0 | Canceled | - | - |
| 9 | 2015-11-07 | Texas Southern | 15 | Grambling | 41 | Final | L | -26 |
| 10 | 2015-11-14 | Alcorn State | 65 | Texas Southern | 13 | Final | L | -52 |
| 11 | 2015-11-28 | Texas Southern | 7 | Alabama A&M | 38 | Final | L | -31 |