Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2013-08-31 | Purdue (65) | 7 | Cincinnati (37) | 42 | Final | L | -35 |
| 2 | 2013-09-07 | Indiana State | 14 | Purdue | 20 | Final | W | 6 |
| 3 | 2013-09-14 | Notre Dame (54) | 31 | Purdue (101) | 24 | Final | L | -7 |
| 4 | 2013-09-21 | Purdue (109) | 10 | Wisconsin (64) | 41 | Final | L | -31 |
| 5 | 2013-09-28 | Northern Illinois (37) | 55 | Purdue (108) | 24 | Final | L | -31 |
| 6 | 2013-10-12 | Nebraska (27) | 44 | Purdue (110) | 7 | Final | L | -37 |
| 7 | 2013-10-19 | Purdue (111) | 0 | Michigan State (32) | 14 | Final | L | -14 |
| 8 | 2013-11-02 | Ohio State (4) | 56 | Purdue (110) | 0 | Final | L | -56 |
| 9 | 2013-11-09 | Iowa (48) | 38 | Purdue (107) | 14 | Final | L | -24 |
| 10 | 2013-11-16 | Purdue (108) | 21 | Penn State (54) | 45 | Final | L | -24 |
| 11 | 2013-11-23 | Illinois (89) | 20 | Purdue (106) | 16 | Final | L | -4 |
| 12 | 2013-11-30 | Purdue (108) | 36 | Indiana (64) | 56 | Final | L | -20 |