Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-08-31 | Tulsa (32) | 24 | Oklahoma State (18) | 59 | Final | W | 35 |
| 2 | 2017-09-08 | Oklahoma State (18) | 44 | South Alabama (97) | 7 | Final | W | 37 |
| 3 | 2017-09-16 | Oklahoma State | 59 | Pittsburgh | 21 | Final | W | 38 |
| 4 | 2017-09-23 | TCU (63) | 44 | Oklahoma State (18) | 31 | Final | L | -13 |
| 5 | 2017-09-30 | Oklahoma State (20) | 41 | Texas Tech (10) | 34 | Final | W | 7 |
| 6 | 2017-10-14 | Baylor (154) | 16 | Oklahoma State (7) | 59 | Final | W | 43 |
| 7 | 2017-10-21 | Oklahoma State (13) | 13 | Texas (53) | 10 | Final/OT | W | 3 |
| 8 | 2017-10-28 | Oklahoma State (11) | 50 | West Virginia (37) | 39 | Final | W | 11 |
| 9 | 2017-11-04 | Oklahoma (11) | 62 | Oklahoma State (12) | 52 | Final | L | -10 |
| 10 | 2017-11-11 | Oklahoma State (16) | 49 | Iowa State (25) | 42 | Final | W | 7 |
| 11 | 2017-11-18 | Kansas State (77) | 45 | Oklahoma State (14) | 40 | Final | L | -5 |
| 12 | 2017-11-25 | Kansas (160) | 17 | Oklahoma State (21) | 58 | Final | W | 41 |
| 13 | 2017-12-28 | Virginia Tech (20) | 21 | Oklahoma State (21) | 30 | Final | W | 9 |