Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2013-09-01 | Ohio (75) | 7 | Louisville (38) | 49 | Final | W | 42 |
| 2 | 2013-09-07 | Eastern Kentucky | 7 | Louisville | 44 | Final | W | 37 |
| 3 | 2013-09-14 | Louisville (11) | 27 | Kentucky (68) | 13 | Final | W | 14 |
| 4 | 2013-09-21 | Florida International | 0 | Louisville | 72 | Final | W | 72 |
| 5 | 2013-10-05 | Louisville (8) | 30 | Temple (119) | 7 | Final | W | 23 |
| 6 | 2013-10-10 | Rutgers (39) | 10 | Louisville (13) | 24 | Final | W | 14 |
| 7 | 2013-10-18 | Central Florida | 38 | Louisville | 35 | Final | L | -3 |
| 8 | 2013-10-26 | Louisville (17) | 34 | South Florida (108) | 3 | Final | W | 31 |
| 9 | 2013-11-08 | Louisville (19) | 31 | Connecticut (121) | 10 | Final | W | 21 |
| 10 | 2013-11-16 | Houston (31) | 13 | Louisville (21) | 20 | Final | W | 7 |
| 11 | 2013-11-23 | Memphis (79) | 17 | Louisville (20) | 24 | Final | W | 7 |
| 12 | 2013-12-05 | Louisville (21) | 31 | Cincinnati (61) | 24 | Final/OT | W | 7 |
| 13 | 2013-12-28 | Miami | 9 | Louisville | 36 | Final | W | 27 |