Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2026-09-05 | Southeast Missouri State (218) | Iowa State (34) | Scheduled - 12:00 PM | - | - | ||
| 2 | 2026-09-12 | Iowa State | Iowa | Scheduled - 6:30 PM | - | - | ||
| 3 | 2026-09-19 | Bowling Green | Iowa State | Scheduled - 11:00 AM | - | - | ||
| 4 | 2026-09-25 | Utah | Iowa State | Scheduled - TBD | - | - | ||
| 5 | 2026-10-02 | West Virginia | Iowa State | Scheduled - TBD | - | - | ||
| 6 | 2026-10-09 | Iowa State | BYU | Scheduled - 8:15 PM | - | - | ||
| 7 | 2026-10-23 | Iowa State | Arizona | Scheduled - TBD | - | - | ||
| 8 | 2026-10-30 | Oklahoma State | Iowa State | Scheduled - TBD | - | - | ||
| 9 | 2026-11-06 | Iowa State | Baylor | Scheduled - TBD | - | - | ||
| 10 | 2026-11-13 | Cincinnati | Iowa State | Scheduled - TBD | - | - | ||
| 11 | 2026-11-20 | Iowa State | Central Florida | Scheduled - 6:00 PM | - | - | ||
| 12 | 2026-11-27 | Kansas State | Iowa State | Scheduled - TBD | - | - |