Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-09-01 | Southwest Baptist | 7 | Houston Baptist | 49 | Final | W | 42 |
| 2 | 2018-09-08 | McNeese State | 51 | Houston Baptist | 34 | Final | L | -17 |
| 3 | 2018-09-15 | Abilene Christian | 38 | Houston Baptist | 13 | Final | L | -25 |
| 4 | 2018-09-29 | Houston Baptist (231) | 27 | SMU (93) | 63 | Final | L | -36 |
| 5 | 2018-10-06 | Houston Baptist (233) | 35 | Central Arkansas (169) | 66 | Final | L | -31 |
| 6 | 2018-10-13 | Houston Baptist (241) | 52 | Southeastern Louisiana (186) | 62 | Final | L | -10 |
| 7 | 2018-10-20 | Stephen F. Austin (225) | 42 | Houston Baptist (242) | 14 | Final | L | -28 |
| 8 | 2018-10-27 | Houston Baptist (245) | 28 | Northwestern State (210) | 31 | Final | L | -3 |
| 9 | 2018-11-03 | Nicholls State (134) | 41 | Houston Baptist (246) | 20 | Final | L | -21 |
| 10 | 2018-11-10 | Houston Baptist (249) | 9 | Lamar (178) | 38 | Final | L | -29 |
| 11 | 2018-11-17 | Sam Houston State (181) | 42 | Houston Baptist (248) | 20 | Final | L | -22 |