Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Sul Ross State | 0 | UTRGV | 66 | Final | W | 66 |
| 2 | 2025-09-06 | UTRGV | 27 | Prairie View A&M (236) | 21 | Final | W | 6 |
| 3 | 2025-09-13 | Langston | 0 | UTRGV | 80 | Final | W | 80 |
| 4 | 2025-09-20 | Texas Wesleyan | 13 | UTRGV (148) | 61 | Final | W | 48 |
| 5 | 2025-09-27 | UTRGV (159) | 31 | Southeastern Louisiana (150) | 45 | Final | L | -14 |
| 6 | 2025-10-04 | Houston Christian (237) | 7 | UTRGV (154) | 27 | Final | W | 20 |
| 7 | 2025-10-18 | UTRGV (163) | 21 | Lamar (140) | 23 | Final | L | -2 |
| 8 | 2025-10-25 | Incarnate Word (217) | UTRGV (163) | Scheduled – 7:00 PM | – | – | ||
| 9 | 2025-11-01 | UTRGV | 0 | Stephen F. Austin (163) | 0 | Scheduled – 6:00 PM | – | – |
| 10 | 2025-11-08 | Nicholls State (207) | 0 | UTRGV | 0 | Scheduled – 5:00 PM | – | – |
| 11 | 2025-11-15 | UTRGV | 0 | McNeese (185) | 0 | Scheduled – 6:00 PM | – | – |
| 12 | 2025-11-22 | East Texas A&M (235) | 0 | UTRGV | 0 | Scheduled – 5:00 PM | – | – |