Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Austin Peay (203) | 34 | Middle Tennessee (150) | 14 | Final | L | -20 |
| 2 | 2025-09-06 | Middle Tennessee (150) | 10 | Wisconsin (64) | 42 | Final | L | -32 |
| 3 | 2025-09-13 | Middle Tennessee (150) | 14 | Nevada (121) | 13 | Final | W | 1 |
| 4 | 2025-09-20 | Marshall (132) | 42 | Middle Tennessee (123) | 28 | Final | L | -14 |
| 5 | 2025-09-27 | Middle Tennessee (144) | 16 | Kennesaw State (91) | 24 | Final | L | -8 |
| 6 | 2025-10-08 | Missouri State (101) | 22 | Middle Tennessee (149) | 20 | Final | L | -2 |
| 7 | 2025-10-22 | Middle Tennessee (147) | Delaware (89) | Scheduled – 7:30 PM | – | – | ||
| 8 | 2025-10-29 | Jacksonville State (75) | 0 | Middle Tennessee (150) | 0 | Scheduled – 6:30 PM | – | – |
| 9 | 2025-11-08 | Florida International (129) | 0 | Middle Tennessee (150) | 0 | Scheduled – 2:00 PM | – | – |
| 10 | 2025-11-15 | Middle Tennessee (150) | 0 | Western Kentucky (94) | 0 | Scheduled – 2:30 PM | – | – |
| 11 | 2025-11-22 | Sam Houston State (65) | 0 | Middle Tennessee (150) | 0 | Scheduled – 2:00 PM | – | – |
| 12 | 2025-11-29 | Middle Tennessee (150) | 0 | New Mexico State (149) | 0 | Scheduled – 1:00 PM | – | – |