Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-11-14 | Southern Miss (301) | 49 | 67 | Memphis (84) | Final | L | -18 |
| 2 | 2015-11-17 | Jackson State (321) | 78 | 60 | Southern Miss (301) | Final | L | -18 |
| 3 | 2015-11-23 | William Carey | 84 | 78 | Southern Miss (301) | Final | L | -6 |
| 4 | 2015-11-28 | Southern Miss (301) | 46 | 61 | Morehead State (195) | Final | L | -15 |
| 5 | 2015-12-01 | Southern Miss (301) | 59 | 69 | Troy (306) | Final | L | -10 |
| 6 | 2015-12-04 | Alabama (68) | 58 | 55 | Southern Miss (301) | Final | L | -3 |
| 7 | 2015-12-06 | North Dakota State (147) | 62 | 74 | Southern Miss (301) | Final | W | 12 |
| 8 | 2015-12-14 | Southern Miss (285) | 57 | 54 | South Alabama (278) | Final | W | 3 |
| 9 | 2015-12-19 | Georgia State (188) | 66 | 46 | Southern Miss (268) | Final | L | -20 |
| 10 | 2015-12-22 | Southern Miss (265) | 40 | 59 | Tulane (207) | Final | L | -19 |
| 11 | 2015-12-29 | SE Oklahoma State | 52 | 66 | Southern Miss (277) | Final | W | 14 |
| 12 | 2016-01-02 | Southern Miss (277) | 57 | 87 | Louisiana Tech (65) | Final | L | -30 |
| 13 | 2016-01-07 | Charlotte (255) | 82 | 76 | Southern Miss (292) | Final | L | -6 |
| 14 | 2016-01-09 | Old Dominion (121) | 71 | 73 | Southern Miss (292) | Final | W | 2 |
| 15 | 2016-01-14 | Southern Miss (273) | 51 | 58 | Florida Atlantic (329) | Final | L | -7 |
| 16 | 2016-01-16 | Southern Miss (273) | 66 | 60 | Florida International (225) | Final | W | 6 |
| 17 | 2016-01-23 | Louisiana Tech (120) | 70 | 59 | Southern Miss (277) | Final | L | -11 |
| 18 | 2016-01-28 | UTEP (194) | 58 | 71 | Southern Miss (282) | Final | W | 13 |
| 19 | 2016-01-30 | UTSA (336) | 70 | 86 | Southern Miss (282) | Final | W | 16 |
| 20 | 2016-02-04 | Southern Miss (263) | 54 | 70 | North Texas (301) | Final | L | -16 |
| 21 | 2016-02-06 | Southern Miss (263) | 65 | 72 | Rice (290) | Final | L | -7 |
| 22 | 2016-02-11 | UAB (81) | 80 | 77 | Southern Miss (289) | Final/2OT | L | -3 |
| 23 | 2016-02-13 | Middle Tennessee (111) | 76 | 54 | Southern Miss (289) | Final | L | -22 |
| 24 | 2016-02-18 | Southern Miss (292) | 73 | 78 | UTEP (188) | Final | L | -5 |
| 25 | 2016-02-20 | Southern Miss (292) | 53 | 74 | UTSA (346) | Final | L | -21 |
| 26 | 2016-02-25 | Rice (258) | 76 | 74 | Southern Miss (298) | Final/OT | L | -2 |
| 27 | 2016-02-27 | North Texas (267) | 70 | 81 | Southern Miss (298) | Final | W | 11 |
| 28 | 2016-03-03 | Southern Miss (296) | 60 | 75 | Western Kentucky (193) | Final | L | -15 |
| 29 | 2016-03-05 | Southern Miss (296) | 106 | 108 | Marshall (152) | Final/OT | L | -2 |