Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-11-10 | Missouri Baptist | 69 | 81 | Southeast Missouri State (247) | Final | W | 12 |
| 2 | 2017-11-13 | Southeast Missouri State (247) | 95 | 96 | Louisiana Tech (115) | Final/OT | L | -1 |
| 3 | 2017-11-16 | Southeast Missouri State (247) | 50 | 66 | Evansville (164) | Final | L | -16 |
| 4 | 2017-11-21 | Cal State-Northridge (293) | 59 | 74 | Southeast Missouri State (270) | Final | W | 15 |
| 5 | 2017-11-22 | Southeast Missouri State (270) | 82 | 88 | Montana State (257) | Final | L | -6 |
| 6 | 2017-11-26 | North Carolina Central (304) | 77 | 70 | Southeast Missouri State (270) | Final | L | -7 |
| 7 | 2017-11-28 | Hannibal-LaGrange | 59 | 83 | Southeast Missouri State (304) | Final | W | 24 |
| 8 | 2017-12-02 | Southeast Missouri State (304) | 86 | 77 | North Carolina Central (300) | Final | W | 9 |
| 9 | 2017-12-06 | UMKC (246) | 87 | 91 | Southeast Missouri State (273) | Final | W | 4 |
| 10 | 2017-12-09 | Southeast Missouri State (273) | 75 | 69 | Southern Illinois (170) | Final | W | 6 |
| 11 | 2017-12-16 | Southeast Missouri State (233) | 71 | 89 | Kansas State (62) | Final | L | -18 |
| 12 | 2017-12-20 | Bradley (98) | 75 | 67 | Southeast Missouri State (238) | Final | L | -8 |
| 13 | 2017-12-22 | Southeast Missouri State (238) | 48 | 78 | Saint Louis (176) | Final | L | -30 |
| 14 | 2017-12-28 | Belmont (91) | 94 | 72 | Southeast Missouri State (259) | Final | L | -22 |
| 15 | 2017-12-31 | Tennessee State (234) | 65 | 77 | Southeast Missouri State (259) | Final | W | 12 |
| 16 | 2018-01-04 | Southeast Missouri State (247) | 73 | 89 | Murray State (84) | Final | L | -16 |
| 17 | 2018-01-06 | Southeast Missouri State (247) | 71 | 76 | Austin Peay (192) | Final | L | -5 |
| 18 | 2018-01-11 | Morehead State (303) | 75 | 78 | Southeast Missouri State (255) | Final | W | 3 |
| 19 | 2018-01-13 | Eastern Kentucky (301) | 91 | 86 | Southeast Missouri State (255) | Final | L | -5 |
| 20 | 2018-01-18 | Southeast Missouri State (268) | 86 | 74 | SIU-Edwardsville (251) | Final | W | 12 |
| 21 | 2018-01-20 | Southeast Missouri State (268) | 86 | 74 | Eastern Illinois (277) | Final | W | 12 |
| 22 | 2018-01-25 | Southeast Missouri State (243) | 65 | 76 | Tennessee Tech (183) | Final | L | -11 |
| 23 | 2018-01-27 | Southeast Missouri State (243) | 60 | 78 | Jacksonville State (138) | Final | L | -18 |
| 24 | 2018-02-01 | Murray State (82) | 87 | 75 | Southeast Missouri State (255) | Final | L | -12 |
| 25 | 2018-02-03 | Austin Peay (184) | 96 | 81 | Southeast Missouri State (255) | Final | L | -15 |
| 26 | 2018-02-08 | Southeast Missouri State (263) | 78 | 62 | Morehead State (294) | Final | W | 16 |
| 27 | 2018-02-10 | Southeast Missouri State (263) | 81 | 77 | Tennessee-Martin (301) | Final/OT | W | 4 |
| 28 | 2018-02-15 | Eastern Illinois (271) | 73 | 80 | Southeast Missouri State (252) | Final | W | 7 |
| 29 | 2018-02-17 | SIU-Edwardsville (287) | 74 | 79 | Southeast Missouri State (252) | Final | W | 5 |
| 30 | 2018-02-22 | Southeast Missouri State (240) | 88 | 91 | Eastern Kentucky (291) | Final | L | -3 |
| 31 | 2018-02-24 | Tennessee-Martin (310) | 72 | 66 | Southeast Missouri State (240) | Final | L | -6 |