Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2026-11-02 | Memphis | Iowa State | Scheduled - TBD | - | - | ||
| 2 | 2026-11-06 | Southern Miss | Iowa State | Scheduled - 7:00 PM | - | - | ||
| 3 | 2026-11-10 | Southern | Iowa State | Scheduled - TBD | - | - | ||
| 4 | 2026-11-15 | Niagara | Iowa State | Scheduled - TBD | - | - | ||
| 5 | 2026-11-24 | San Diego State | Iowa State | Scheduled - 2:30 PM | - | - | ||
| 6 | 2026-12-01 | Alcorn State | Iowa State | Scheduled - TBD | - | - | ||
| 7 | 2026-12-02 | Alcorn State | Iowa State | Scheduled - TBD | - | - | ||
| 8 | 2026-12-06 | Purdue | Iowa State | Scheduled - TBD | - | - | ||
| 9 | 2026-12-10 | Iowa State | Iowa | Scheduled - 6:00 PM | - | - | ||
| 10 | 2026-12-13 | North Carolina Central | Iowa State | Scheduled - TBD | - | - | ||
| 11 | 2026-12-18 | Iowa State | Missouri State | Scheduled - TBD | - | - | ||
| 12 | 2026-12-21 | Northern Arizona | Iowa State | Scheduled - TBD | - | - | ||
| 13 | 2026-12-29 | New Hampshire | Iowa State | Scheduled - TBD | - | - | ||
| 14 | 2027-01-02 | Arizona | Iowa State | Scheduled - TBD | - | - | ||
| 15 | 2027-01-05 | Iowa State | Colorado | Scheduled - TBD | - | - | ||
| 16 | 2027-01-09 | Oklahoma State | Iowa State | Scheduled - TBD | - | - | ||
| 17 | 2027-01-13 | Iowa State | Houston | Scheduled - TBD | - | - | ||
| 18 | 2027-01-16 | Iowa State | Texas Tech | Scheduled - TBD | - | - | ||
| 19 | 2027-01-20 | BYU | Iowa State | Scheduled - TBD | - | - | ||
| 20 | 2027-01-23 | Iowa State | Central Florida | Scheduled - TBD | - | - | ||
| 21 | 2027-01-30 | Kansas State | Iowa State | Scheduled - TBD | - | - | ||
| 22 | 2027-02-02 | Utah | Iowa State | Scheduled - TBD | - | - | ||
| 23 | 2027-02-06 | Iowa State | West Virginia | Scheduled - TBD | - | - | ||
| 24 | 2027-02-10 | Iowa State | Oklahoma State | Scheduled - TBD | - | - | ||
| 25 | 2027-02-13 | Kansas | Iowa State | Scheduled - TBD | - | - | ||
| 26 | 2027-02-16 | Cincinnati | Iowa State | Scheduled - TBD | - | - | ||
| 27 | 2027-02-19 | Iowa State | Arizona State | Scheduled - TBD | - | - | ||
| 28 | 2027-02-23 | Iowa State | Baylor | Scheduled - TBD | - | - | ||
| 29 | 2027-02-27 | TCU | Iowa State | Scheduled - TBD | - | - | ||
| 30 | 2027-03-01 | Iowa State | Kansas | Scheduled - 8:00 PM | - | - | ||
| 31 | 2027-03-06 | West Virginia | Iowa State | Scheduled - TBD | - | - |