Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-11-10 | McNeese State (332) | 53 | 81 | Houston (59) | Final | W | 28 |
| 2 | 2017-11-17 | Drexel (285) | 84 | 80 | Houston (59) | Final | L | -4 |
| 3 | 2017-11-18 | Houston (59) | 68 | 66 | Liberty (186) | Final | W | 2 |
| 4 | 2017-11-19 | Houston (59) | 78 | 73 | Wake Forest (46) | Final | W | 5 |
| 5 | 2017-11-25 | Incarnate Word (175) | 58 | 97 | Houston (123) | Final | W | 39 |
| 6 | 2017-11-29 | New Orleans (326) | 66 | 75 | Houston (92) | Final | W | 9 |
| 7 | 2017-12-02 | Arkansas (20) | 65 | 91 | Houston (92) | Final | W | 26 |
| 8 | 2017-12-06 | Fairfield (232) | 66 | 88 | Houston (52) | Final | W | 22 |
| 9 | 2017-12-09 | Houston (52) | 77 | 58 | Saint Louis (204) | Final | W | 19 |
| 10 | 2017-12-13 | Houston (34) | 77 | 80 | LSU (104) | Final | L | -3 |
| 11 | 2017-12-17 | Prairie View A&M (245) | 72 | 92 | Houston (34) | Final | W | 20 |
| 12 | 2017-12-20 | Houston (51) | 70 | 59 | Providence (66) | Final | W | 11 |
| 13 | 2017-12-28 | Houston (45) | 79 | 60 | South Florida (246) | Final | W | 19 |
| 14 | 2017-12-30 | Temple (65) | 73 | 76 | Houston (45) | Final | W | 3 |
| 15 | 2018-01-04 | Houston (35) | 63 | 81 | Wichita State (19) | Final | L | -18 |
| 16 | 2018-01-11 | Tulsa (107) | 71 | 104 | Houston (42) | Final | W | 33 |
| 17 | 2018-01-14 | Houston (42) | 65 | 49 | East Carolina (268) | Final | W | 16 |
| 18 | 2018-01-17 | Houston (37) | 72 | 81 | Tulane (102) | Final | L | -9 |
| 19 | 2018-01-20 | Wichita State (13) | 59 | 73 | Houston (37) | Final | W | 14 |
| 20 | 2018-01-28 | South Florida (280) | 40 | 63 | Houston (42) | Final | W | 23 |
| 21 | 2018-01-31 | Houston (41) | 70 | 80 | Cincinnati (7) | Final | L | -10 |
| 22 | 2018-02-03 | Houston (41) | 69 | 65 | Central Florida (79) | Final | W | 4 |
| 23 | 2018-02-08 | SMU (57) | 58 | 67 | Houston (37) | Final | W | 9 |
| 24 | 2018-02-11 | Tulane (111) | 42 | 73 | Houston (37) | Final | W | 31 |
| 25 | 2018-02-15 | Cincinnati (3) | 62 | 67 | Houston (31) | Final | W | 5 |
| 26 | 2018-02-18 | Houston (31) | 80 | 59 | Temple (66) | Final | W | 21 |
| 27 | 2018-02-22 | Houston (20) | 85 | 91 | Memphis (105) | Final | L | -6 |
| 28 | 2018-02-25 | East Carolina (236) | 58 | 109 | Houston (20) | Final | W | 51 |
| 29 | 2018-02-28 | Houston (25) | 69 | 56 | SMU (74) | Final | W | 13 |
| 30 | 2018-03-04 | Connecticut (124) | 71 | 81 | Houston (25) | Final | W | 10 |
| 31 | 2018-03-09 | Central Florida (80) | 56 | 84 | Houston (21) | Final | W | 28 |
| 32 | 2018-03-10 | Houston (21) | 77 | 74 | Wichita State (16) | Final | W | 3 |
| 33 | 2018-03-11 | Houston (21) | 55 | 56 | Cincinnati (6) | Final | L | -1 |
| 34 | 2018-03-17 | Houston (9) | 63 | 64 | Michigan (45) | Final - 0:00 | L | -1 |