Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-28 | North Carolina Wesleyan | 68 | 117 | Coastal Carolina (188) | Final | W | 49 |
| 2 | 2020-12-03 | Columbia International | 56 | 113 | Coastal Carolina (188) | Final | W | 57 |
| 3 | 2020-12-07 | North Carolina Central (341) | 71 | 78 | Coastal Carolina (188) | Final | W | 7 |
| 4 | 2020-12-12 | Greensboro | 45 | 103 | Coastal Carolina (188) | Final | W | 58 |
| 5 | 2020-12-15 | Coastal Carolina (188) | 77 | 88 | Wofford (221) | Final | L | -11 |
| 6 | 2020-12-17 | Delaware State (361) | 73 | 99 | Coastal Carolina (188) | Final | W | 26 |
| 7 | 2020-12-18 | Alice Lloyd | 63 | 86 | Coastal Carolina (188) | Final | W | 23 |
| 8 | 2021-01-01 | Georgia State (299) | 69 | 81 | Coastal Carolina (188) | Final | W | 12 |
| 9 | 2021-01-02 | Georgia State (299) | 70 | 62 | Coastal Carolina (188) | Final | L | -8 |
| 10 | 2021-01-08 | South Alabama (177) | 65 | 78 | Coastal Carolina (188) | Final | W | 13 |
| 11 | 2021-01-09 | South Alabama (177) | 69 | 83 | Coastal Carolina (188) | Final | W | 14 |
| 12 | 2021-01-15 | Coastal Carolina (188) | 0 | 0 | Georgia State (299) | Cancelled | - | - |
| 13 | 2021-01-16 | Coastal Carolina (188) | 68 | 71 | Georgia State (299) | Final | L | -3 |
| 14 | 2021-01-22 | Troy (127) | 81 | 90 | Coastal Carolina (188) | Final | W | 9 |
| 15 | 2021-01-23 | Troy (127) | 65 | 70 | Coastal Carolina (188) | Final | W | 5 |
| 16 | 2021-01-29 | Coastal Carolina (188) | 79 | 62 | Georgia Southern (216) | Final | W | 17 |
| 17 | 2021-01-30 | Coastal Carolina (188) | 58 | 61 | Georgia Southern (216) | Final | L | -3 |
| 18 | 2021-02-05 | Coastal Carolina (188) | 65 | 71 | South Alabama (177) | Final | L | -6 |
| 19 | 2021-02-06 | Coastal Carolina (188) | 66 | 70 | South Alabama (177) | Final | L | -4 |
| 20 | 2021-02-11 | Coastal Carolina (188) | 0 | 0 | Appalachian State (159) | Cancelled | - | - |
| 21 | 2021-02-13 | Appalachian State (159) | 0 | 0 | Coastal Carolina (188) | Cancelled | - | - |
| 22 | 2021-02-19 | Georgia Southern (216) | 0 | 0 | Coastal Carolina (188) | Cancelled | - | - |
| 23 | 2021-02-21 | Georgia Southern (216) | 55 | 65 | Coastal Carolina (188) | Final | W | 10 |
| 24 | 2021-02-26 | Coastal Carolina (188) | 75 | 59 | Troy (127) | Final | W | 16 |
| 25 | 2021-02-27 | Coastal Carolina (188) | 76 | 71 | Troy (127) | Final | W | 5 |
| 26 | 2021-03-06 | Troy (127) | 68 | 86 | Coastal Carolina (188) | Final | W | 18 |
| 27 | 2021-03-07 | Appalachian State (159) | 64 | 61 | Coastal Carolina (188) | Final/OT | L | -3 |
| 28 | 2021-03-22 | Coastal Carolina (123) | 93 | 82 | Bryant (118) | Final | W | 11 |
| 29 | 2021-03-23 | Stetson (236) | 72 | 77 | Coastal Carolina (123) | Final (OT) | W | 5 |
| 30 | 2021-03-24 | Coastal Carolina (123) | 61 | 84 | Pepperdine (104) | Final | L | -23 |