Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-11-11 | Canisius (184) | 75 | 80 | Buffalo (157) | Final | W | 5 |
| 2 | 2017-11-15 | Jacksonville State (191) | 76 | 81 | Buffalo (157) | Final | W | 5 |
| 3 | 2017-11-20 | Buffalo (157) | 67 | 73 | Cincinnati (20) | Final | L | -6 |
| 4 | 2017-11-21 | UAB (77) | 91 | 96 | Buffalo (68) | Final/OT | W | 5 |
| 5 | 2017-11-22 | South Dakota State (133) | 94 | 80 | Buffalo (68) | Final | L | -14 |
| 6 | 2017-11-29 | Buffalo (118) | 106 | 87 | Niagara (215) | Final | W | 19 |
| 7 | 2017-12-02 | St. Bonaventure (108) | 73 | 62 | Buffalo (118) | Final | L | -11 |
| 8 | 2017-12-06 | Buffalo (121) | 75 | 72 | Delaware (268) | Final | W | 3 |
| 9 | 2017-12-09 | Central Penn | 54 | 88 | Buffalo (121) | Final | W | 34 |
| 10 | 2017-12-16 | Robert Morris (164) | 70 | 86 | Buffalo (118) | Final | W | 16 |
| 11 | 2017-12-19 | Buffalo (106) | 74 | 81 | Syracuse (23) | Final | L | -7 |
| 12 | 2017-12-21 | Buffalo (106) | 73 | 89 | Texas A&M (9) | Final | L | -16 |
| 13 | 2017-12-28 | NJIT (197) | 81 | 86 | Buffalo (101) | Final/OT | W | 5 |
| 14 | 2018-01-02 | Toledo (154) | 94 | 104 | Buffalo (93) | Final | W | 10 |
| 15 | 2018-01-06 | Buffalo (93) | 83 | 63 | Ball State (126) | Final | W | 20 |
| 16 | 2018-01-09 | Buffalo (80) | 87 | 65 | Akron (219) | Final | W | 22 |
| 17 | 2018-01-13 | Miami (OH) (185) | 66 | 82 | Buffalo (80) | Final | W | 16 |
| 18 | 2018-01-16 | Northern Illinois (210) | 67 | 95 | Buffalo (70) | Final | W | 28 |
| 19 | 2018-01-19 | Buffalo (70) | 84 | 74 | Western Michigan (165) | Final | W | 10 |
| 20 | 2018-01-23 | Eastern Michigan (207) | 69 | 83 | Buffalo (65) | Final | W | 14 |
| 21 | 2018-01-26 | Buffalo (65) | 73 | 66 | Ohio (192) | Final | W | 7 |
| 22 | 2018-01-30 | Buffalo (65) | 79 | 82 | Kent State (186) | Final | L | -3 |
| 23 | 2018-02-02 | Western Michigan (173) | 86 | 92 | Buffalo (65) | Final | W | 6 |
| 24 | 2018-02-06 | Buffalo (72) | 88 | 82 | Central Michigan (170) | Final | W | 6 |
| 25 | 2018-02-10 | Buffalo (72) | 88 | 90 | Northern Illinois (239) | Final/OT | L | -2 |
| 26 | 2018-02-13 | Kent State (191) | 72 | 84 | Buffalo (80) | Final | W | 12 |
| 27 | 2018-02-16 | Bowling Green (190) | 82 | 95 | Buffalo (80) | Final | W | 13 |
| 28 | 2018-02-20 | Buffalo (74) | 81 | 84 | Miami (OH) (186) | Final | L | -3 |
| 29 | 2018-02-24 | Ohio (212) | 82 | 108 | Buffalo (74) | Final | W | 26 |
| 30 | 2018-02-27 | Akron (229) | 68 | 80 | Buffalo (76) | Final | W | 12 |
| 31 | 2018-03-02 | Buffalo (76) | 100 | 70 | Bowling Green (201) | Final | W | 30 |
| 32 | 2018-03-08 | Central Michigan (172) | 74 | 89 | Buffalo (72) | Final | W | 15 |
| 33 | 2018-03-09 | Kent State (191) | 61 | 78 | Buffalo (72) | Final | W | 17 |
| 34 | 2018-03-10 | Toledo (112) | 66 | 76 | Buffalo (72) | Final | W | 10 |
| 35 | 2018-03-17 | Buffalo (132) | 75 | 95 | Kentucky (8) | Final - 0:00 | L | -20 |