Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Winthrop (257) | 68 | 93 | Penn State (54) | Final | L | -25 |
| 2 | 2022-11-09 | Piedmont | 56 | 78 | Winthrop (257) | Final | W | 22 |
| 3 | 2022-11-12 | Middle Tennessee (123) | 68 | 76 | Winthrop (257) | Final | W | 8 |
| 4 | 2022-11-15 | Winthrop (257) | 65 | 89 | Auburn (32) | Final | L | -24 |
| 5 | 2022-11-19 | Winthrop (133) | 68 | 77 | Mercer (174) | Final | L | -9 |
| 6 | 2022-11-22 | Southern Miss (78) | 77 | 52 | Winthrop (257) | Final | L | -25 |
| 7 | 2022-11-23 | Eastern Michigan (335) | 87 | 101 | Winthrop (257) | Final | W | 14 |
| 8 | 2022-11-29 | Toccoa Falls | 52 | 99 | Winthrop (257) | Final | W | 47 |
| 9 | 2022-12-03 | Coastal Carolina (188) | 86 | 81 | Winthrop (133) | Final | L | -5 |
| 10 | 2022-12-06 | South Carolina State (355) | 67 | 81 | Winthrop (133) | Final | W | 14 |
| 11 | 2022-12-10 | Winthrop (257) | 67 | 82 | Furman (105) | Final | L | -15 |
| 12 | 2022-12-17 | Winthrop (257) | 81 | 89 | LSU (122) | Final | L | -8 |
| 13 | 2022-12-21 | Winthrop (133) | 57 | 74 | Duquesne (121) | Final | L | -17 |
| 14 | 2022-12-29 | Winthrop (133) | 62 | 70 | South Carolina Upstate (293) | Final | L | -8 |
| 15 | 2022-12-31 | UNC-Asheville (130) | 60 | 62 | Winthrop (257) | Final | W | 2 |
| 16 | 2023-01-04 | Presbyterian (357) | 72 | 82 | Winthrop (257) | Final | W | 10 |
| 17 | 2023-01-07 | Winthrop (257) | 71 | 85 | Longwood (180) | Final | L | -14 |
| 18 | 2023-01-11 | Radford (188) | 66 | 52 | Winthrop (257) | Final | L | -14 |
| 19 | 2023-01-14 | Winthrop (257) | 78 | 74 | Campbell (255) | Final | W | 4 |
| 20 | 2023-01-18 | Winthrop (257) | 66 | 71 | High Point (276) | Final | L | -5 |
| 21 | 2023-01-21 | Gardner-Webb (210) | 63 | 61 | Winthrop (257) | Final | L | -2 |
| 22 | 2023-01-25 | Charleston Southern (324) | 64 | 76 | Winthrop (257) | Final | W | 12 |
| 23 | 2023-01-28 | Winthrop (257) | 76 | 58 | Presbyterian (357) | Final | W | 18 |
| 24 | 2023-02-01 | Longwood (180) | 74 | 76 | Winthrop (257) | Final | W | 2 |
| 25 | 2023-02-04 | Winthrop (257) | 66 | 69 | Radford (188) | Final | L | -3 |
| 26 | 2023-02-08 | Winthrop (257) | 79 | 86 | UNC-Asheville (130) | Final | L | -7 |
| 27 | 2023-02-11 | South Carolina Upstate (293) | 79 | 70 | Winthrop (133) | Final | L | -9 |
| 28 | 2023-02-15 | Winthrop (133) | 86 | 78 | Gardner-Webb (363) | Final | W | 8 |
| 29 | 2023-02-18 | Winthrop (133) | 75 | 67 | Charleston Southern (262) | Final | W | 8 |
| 30 | 2023-02-22 | Campbell (191) | 93 | 95 | Winthrop (133) | Final/OT | W | 2 |
| 31 | 2023-02-25 | High Point (271) | 78 | 84 | Winthrop (243) | Final | W | 6 |
| 32 | 2023-03-03 | Winthrop (133) | 69 | 78 | Radford (255) | Final | L | -9 |