Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-11-06 | Morgan State (329) | 77 | 100 | Villanova (2) | Final | W | 23 |
| 2 | 2018-11-10 | Quinnipiac (280) | 53 | 86 | Villanova (2) | Final | W | 33 |
| 3 | 2018-11-14 | Michigan (9) | 73 | 46 | Villanova (41) | Final | L | -27 |
| 4 | 2018-11-17 | Furman (54) | 76 | 68 | Villanova (41) | Final/OT | L | -8 |
| 5 | 2018-11-22 | Villanova (159) | 83 | 56 | Canisius (226) | Final | W | 27 |
| 6 | 2018-11-23 | Villanova (159) | 77 | 58 | Oklahoma State (165) | Final | W | 19 |
| 7 | 2018-11-25 | Villanova (159) | 66 | 60 | Florida State (30) | Final | W | 6 |
| 8 | 2018-12-01 | Villanova (46) | 85 | 78 | La Salle (343) | Final | W | 7 |
| 9 | 2018-12-05 | Temple (51) | 59 | 69 | Villanova (44) | Final | W | 10 |
| 10 | 2018-12-08 | Saint Joseph’s (158) | 58 | 70 | Villanova (44) | Final | W | 12 |
| 11 | 2018-12-11 | Villanova (25) | 75 | 78 | Penn (99) | Final | L | -3 |
| 12 | 2018-12-15 | Villanova (25) | 71 | 74 | Kansas (1) | Final | L | -3 |
| 13 | 2018-12-22 | Connecticut (80) | 58 | 81 | Villanova (39) | Final | W | 23 |
| 14 | 2019-01-02 | DePaul (126) | 68 | 73 | Villanova (36) | Final | W | 5 |
| 15 | 2019-01-05 | Villanova (36) | 65 | 59 | Providence (57) | Final | W | 6 |
| 16 | 2019-01-08 | St. John’s (16) | 71 | 76 | Villanova (36) | Final | W | 5 |
| 17 | 2019-01-13 | Villanova (36) | 90 | 78 | Creighton (44) | Final | W | 12 |
| 18 | 2019-01-18 | Xavier (75) | 75 | 85 | Villanova (22) | Final | W | 10 |
| 19 | 2019-01-22 | Villanova (25) | 80 | 72 | Butler (51) | Final | W | 8 |
| 20 | 2019-01-27 | Seton Hall (47) | 52 | 80 | Villanova (25) | Final | W | 28 |
| 21 | 2019-01-30 | Villanova (17) | 86 | 74 | DePaul (106) | Final | W | 12 |
| 22 | 2019-02-03 | Georgetown (74) | 65 | 77 | Villanova (17) | Final | W | 12 |
| 23 | 2019-02-06 | Creighton (52) | 59 | 66 | Villanova (15) | Final/OT | W | 7 |
| 24 | 2019-02-09 | Villanova (15) | 65 | 66 | Marquette (13) | Final | L | -1 |
| 25 | 2019-02-13 | Providence (75) | 67 | 85 | Villanova (16) | Final | W | 18 |
| 26 | 2019-02-17 | Villanova (16) | 65 | 71 | St. John’s (40) | Final | L | -6 |
| 27 | 2019-02-20 | Villanova (22) | 73 | 85 | Georgetown (74) | Final | L | -12 |
| 28 | 2019-02-24 | Villanova (22) | 54 | 66 | Xavier (91) | Final | L | -12 |
| 29 | 2019-02-27 | Marquette (11) | 61 | 67 | Villanova (30) | Final | W | 6 |
| 30 | 2019-03-02 | Butler (54) | 54 | 75 | Villanova (30) | Final | W | 21 |
| 31 | 2019-03-09 | Villanova (26) | 75 | 79 | Seton Hall (59) | Final | L | -4 |
| 32 | 2019-03-14 | Providence (72) | 62 | 73 | Villanova (27) | Final | W | 11 |
| 33 | 2019-03-15 | Xavier (66) | 67 | 71 | Villanova (27) | Final/OT | W | 4 |
| 34 | 2019-03-16 | Seton Hall (53) | 72 | 74 | Villanova (27) | Final | W | 2 |
| 35 | 2019-03-21 | Saint Mary’s (52) | 57 | 61 | Villanova (25) | Final | W | 4 |
| 36 | 2019-03-23 | Villanova (25) | 61 | 87 | Purdue (15) | Final | L | -26 |