Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | William Carey | 42 | 75 | Southern Miss (78) | Final | W | 33 |
| 2 | 2022-11-11 | Southern Miss (78) | 60 | 48 | Vanderbilt (70) | Final | W | 12 |
| 3 | 2022-11-14 | Loyola New Orleans | 62 | 86 | Southern Miss (201) | Final | W | 24 |
| 4 | 2022-11-14 | Loyola (LA) | 62 | 86 | Southern Miss (78) | Final | W | 24 |
| 5 | 2022-11-18 | Southern Miss (78) | 76 | 72 | Liberty (68) | Final | W | 4 |
| 6 | 2022-11-22 | Southern Miss (78) | 77 | 52 | Winthrop (257) | Final | W | 25 |
| 7 | 2022-11-23 | Purdue Fort Wayne (213) | 58 | 70 | Southern Miss (78) | Final | W | 12 |
| 8 | 2022-11-27 | Mobile | 52 | 103 | Southern Miss (78) | Final | W | 51 |
| 9 | 2022-11-29 | Montana (198) | 54 | 64 | Southern Miss (78) | Final | W | 10 |
| 10 | 2022-12-04 | Southern Miss (78) | 82 | 84 | Northwestern State (165) | Final | L | -2 |
| 11 | 2022-12-10 | Lamar (353) | 59 | 95 | Southern Miss (78) | Final | W | 36 |
| 12 | 2022-12-13 | Southern Miss (201) | 91 | 65 | Lamar (279) | Final | W | 26 |
| 13 | 2022-12-22 | Southern Miss (201) | 63 | 74 | UNLV (105) | Final | L | -11 |
| 14 | 2022-12-29 | Troy (127) | 60 | 64 | Southern Miss (201) | Final | W | 4 |
| 15 | 2022-12-31 | Appalachian State (172) | 70 | 76 | Southern Miss (78) | Final | W | 6 |
| 16 | 2023-01-05 | Southern Miss (78) | 61 | 75 | Louisiana (98) | Final | L | -14 |
| 17 | 2023-01-07 | Southern Miss (78) | 65 | 60 | Louisiana-Monroe (261) | Final | W | 5 |
| 18 | 2023-01-12 | Southern Miss (78) | 67 | 89 | Marshall (77) | Final | L | -22 |
| 19 | 2023-01-14 | Southern Miss (78) | 74 | 57 | Arkansas State (302) | Final | W | 17 |
| 20 | 2023-01-19 | South Alabama (164) | 72 | 76 | Southern Miss (78) | Final | W | 4 |
| 21 | 2023-01-21 | James Madison (99) | 70 | 83 | Southern Miss (78) | Final | W | 13 |
| 22 | 2023-01-26 | Arkansas State (302) | 57 | 73 | Southern Miss (78) | Final | W | 16 |
| 23 | 2023-01-28 | Texas State (246) | 58 | 67 | Southern Miss (78) | Final | W | 9 |
| 24 | 2023-02-02 | Southern Miss (78) | 74 | 65 | Troy (148) | Final | W | 9 |
| 25 | 2023-02-04 | Southern Miss (78) | 79 | 71 | Georgia State (269) | Final | W | 8 |
| 26 | 2023-02-09 | Louisiana (98) | 71 | 82 | Southern Miss (78) | Final | W | 11 |
| 27 | 2023-02-11 | Louisiana-Monroe (358) | 67 | 76 | Southern Miss (201) | Final | W | 9 |
| 28 | 2023-02-16 | Southern Miss (78) | 54 | 85 | South Alabama (164) | Final | L | -31 |
| 29 | 2023-02-18 | Georgia Southern (216) | 62 | 73 | Southern Miss (201) | Final | W | 11 |
| 30 | 2023-02-22 | Southern Miss (201) | 64 | 69 | Old Dominion (254) | Final | L | -5 |
| 31 | 2023-02-24 | Southern Miss (80) | 79 | 69 | Texas State (253) | Final | W | 10 |
| 32 | 2023-03-04 | South Alabama (177) | 78 | 61 | Southern Miss (201) | Final | L | -17 |
| 33 | 2023-03-14 | Southern Miss | 60 | 88 | UAB | Final | L | -28 |