Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-11-06 | William Carey | 0 | 0 | Southern Miss (218) | 11/6 – 11:00 AM EST | – | – |
| 2 | 2018-11-06 | Southeast Baptist | 66 | 111 | Southern Miss (218) | Final | W | 45 |
| 3 | 2018-11-11 | Southern Miss (218) | 74 | 64 | SMU (86) | Final | W | 10 |
| 4 | 2018-11-15 | Southern Miss (55) | 81 | 66 | Troy (237) | Final | W | 15 |
| 5 | 2018-11-20 | North Florida (318) | 64 | 48 | Southern Miss (57) | Final | L | -16 |
| 6 | 2018-11-21 | Southern Miss (57) | 68 | 63 | Western Carolina (317) | Final | W | 5 |
| 7 | 2018-11-25 | William Carey | 78 | 72 | Southern Miss (57) | Final | L | -6 |
| 8 | 2018-11-28 | South Alabama (256) | 67 | 71 | Southern Miss (232) | Final | W | 4 |
| 9 | 2018-12-02 | Rust | 46 | 106 | Southern Miss (232) | Final | W | 60 |
| 10 | 2018-12-11 | Millsaps | 47 | 81 | Southern Miss (181) | Final | W | 34 |
| 11 | 2018-12-15 | Southern Miss (181) | 60 | 63 | Wichita State (131) | Final | L | -3 |
| 12 | 2018-12-19 | Southern Miss (185) | 51 | 55 | Kansas State (43) | Final | L | -4 |
| 13 | 2018-12-21 | Southern Miss (185) | 66 | 60 | South Dakota (216) | Final | W | 6 |
| 14 | 2018-12-29 | Southern Miss (171) | 56 | 71 | Louisiana Tech (121) | Final | L | -15 |
| 15 | 2019-01-03 | Southern Miss (185) | 65 | 73 | Rice (276) | Final | L | -8 |
| 16 | 2019-01-05 | Southern Miss (185) | 62 | 65 | North Texas (47) | Final | L | -3 |
| 17 | 2019-01-10 | Middle Tennessee (310) | 70 | 77 | Southern Miss (206) | Final | W | 7 |
| 18 | 2019-01-12 | UAB (151) | 68 | 73 | Southern Miss (206) | Final | W | 5 |
| 19 | 2019-01-17 | Southern Miss (188) | 63 | 60 | Charlotte (242) | Final | W | 3 |
| 20 | 2019-01-19 | Southern Miss (188) | 60 | 78 | Old Dominion (108) | Final | L | -18 |
| 21 | 2019-01-24 | Western Kentucky (140) | 66 | 63 | Southern Miss (184) | Final | L | -3 |
| 22 | 2019-01-26 | Marshall (94) | 51 | 101 | Southern Miss (184) | Final | W | 50 |
| 23 | 2019-01-31 | Southern Miss (171) | 89 | 73 | Florida International (183) | Final | W | 16 |
| 24 | 2019-02-02 | Southern Miss (171) | 74 | 72 | Florida Atlantic (194) | Final | W | 2 |
| 25 | 2019-02-09 | Louisiana Tech (151) | 71 | 73 | Southern Miss (161) | Final/OT | W | 2 |
| 26 | 2019-02-14 | UTSA (162) | 71 | 78 | Southern Miss (152) | Final | W | 7 |
| 27 | 2019-02-16 | UTEP (265) | 47 | 77 | Southern Miss (152) | Final | W | 30 |
| 28 | 2019-02-23 | UAB (160) | 76 | 72 | Southern Miss (142) | Final/OT | L | -4 |
| 29 | 2019-03-03 | Southern Miss (147) | 71 | 76 | Western Kentucky (128) | Final | L | -5 |
| 30 | 2019-03-06 | Southern Miss (154) | 59 | 52 | Old Dominion (77) | Final | W | 7 |
| 31 | 2019-03-09 | UTSA (173) | 48 | 81 | Southern Miss (154) | Final | W | 33 |
| 32 | 2019-03-14 | Marshall (143) | 73 | 82 | Southern Miss (134) | Final | W | 9 |
| 33 | 2019-03-15 | Southern Miss (134) | 59 | 70 | Western Kentucky (123) | Final | L | -11 |