Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Little Rock (345) | 63 | 94 | Southern Illinois (113) | Final | W | 31 |
| 2 | 2022-11-10 | Southern Illinois (113) | 61 | 60 | Oklahoma State (44) | Final | W | 1 |
| 3 | 2022-11-13 | Southern Illinois (113) | 53 | 71 | Southern Indiana (265) | Final | L | -18 |
| 4 | 2022-11-17 | Tennessee State (266) | 44 | 57 | Southern Illinois (113) | Final | W | 13 |
| 5 | 2022-11-22 | Southern Illinois (113) | 49 | 56 | UNLV (96) | Final | L | -7 |
| 6 | 2022-11-24 | California Baptist (156) | 61 | 64 | Southern Illinois (113) | Final | W | 3 |
| 7 | 2022-11-30 | Southern Illinois (150) | 80 | 53 | Evansville (302) | Final | W | 27 |
| 8 | 2022-12-03 | Southern Illinois (150) | 72 | 85 | Saint Louis (31) | Final | L | -13 |
| 9 | 2022-12-07 | Indiana State (114) | 74 | 71 | Southern Illinois (113) | Final | L | -3 |
| 10 | 2022-12-10 | Alcorn State (235) | 68 | 74 | Southern Illinois (113) | Final | W | 6 |
| 11 | 2022-12-13 | Lincoln (MO) | 51 | 88 | Southern Illinois (150) | Final | W | 37 |
| 12 | 2022-12-16 | Chicago State (351) | 52 | 63 | Southern Illinois (150) | Final | W | 11 |
| 13 | 2022-12-19 | Alabama A&M | 0 | 0 | Southern Illinois | Scheduled - TBA | - | - |
| 14 | 2022-12-21 | Southern Illinois (150) | 70 | 68 | Southeast Missouri State (226) | Final | W | 2 |
| 15 | 2022-12-29 | Southern Illinois (150) | 63 | 57 | Murray State (116) | Final | W | 6 |
| 16 | 2023-01-01 | Belmont (121) | 45 | 63 | Southern Illinois (113) | Final | W | 18 |
| 17 | 2023-01-04 | Drake (64) | 49 | 53 | Southern Illinois (113) | Final | W | 4 |
| 18 | 2023-01-07 | Southern Illinois (113) | 57 | 69 | Northern Iowa (200) | Final | L | -12 |
| 19 | 2023-01-11 | Southern Illinois (113) | 69 | 61 | Indiana State (114) | Final | W | 8 |
| 20 | 2023-01-14 | Illinois State (263) | 57 | 69 | Southern Illinois (113) | Final | W | 12 |
| 21 | 2023-01-17 | Evansville (344) | 70 | 77 | Southern Illinois (113) | Final | W | 7 |
| 22 | 2023-01-21 | Southern Illinois (113) | 61 | 57 | Missouri State (160) | Final | W | 4 |
| 23 | 2023-01-24 | Murray State (179) | 64 | 68 | Southern Illinois (113) | Final | W | 4 |
| 24 | 2023-01-29 | Southern Illinois (113) | 66 | 72 | Illinois State (263) | Final | L | -6 |
| 25 | 2023-02-01 | Southern Illinois (113) | 52 | 62 | Bradley (79) | Final | L | -10 |
| 26 | 2023-02-05 | Missouri State (160) | 53 | 73 | Southern Illinois (113) | Final | W | 20 |
| 27 | 2023-02-08 | Illinois-Chicago (271) | 66 | 68 | Southern Illinois (113) | Final | W | 2 |
| 28 | 2023-02-11 | Southern Illinois (150) | 59 | 82 | Drake (217) | Final | L | -23 |
| 29 | 2023-02-14 | Southern Illinois (113) | 66 | 62 | Valparaiso (268) | Final | W | 4 |
| 30 | 2023-02-19 | Bradley (79) | 50 | 48 | Southern Illinois (113) | Final | L | -2 |
| 31 | 2023-02-22 | Northern Iowa (89) | 63 | 86 | Southern Illinois (150) | Final | W | 23 |
| 32 | 2023-02-26 | Southern Illinois (107) | 68 | 65 | Illinois-Chicago (270) | Final | W | 3 |
| 33 | 2023-03-03 | Missouri State (224) | 51 | 54 | Southern Illinois (150) | Final | W | 3 |
| 34 | 2023-03-04 | Southern Illinois (150) | 52 | 65 | Drake (217) | Final | L | -13 |