Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-11-09 | Southern Illinois (130) | 59 | 71 | Kentucky (18) | Final | L | -12 |
| 2 | 2018-11-12 | Buffalo (68) | 62 | 53 | Southern Illinois (130) | Final | L | -9 |
| 3 | 2018-11-17 | Arkansas-Pine Bluff (326) | 48 | 78 | Southern Illinois (292) | Final | W | 30 |
| 4 | 2018-11-19 | Howard (180) | 69 | 83 | Southern Illinois (292) | Final | W | 14 |
| 5 | 2018-11-22 | Southern Illinois (205) | 62 | 84 | Massachusetts (190) | Final | L | -22 |
| 6 | 2018-11-23 | Southern Illinois (205) | 79 | 69 | Tulsa (77) | Final | W | 10 |
| 7 | 2018-11-27 | Southern Illinois (127) | 82 | 67 | Colorado State (202) | Final | W | 15 |
| 8 | 2018-12-01 | Southern Illinois (127) | 82 | 61 | SIU-Edwardsville (289) | Final | W | 21 |
| 9 | 2018-12-05 | Saint Louis (46) | 56 | 61 | Southern Illinois (107) | Final | W | 5 |
| 10 | 2018-12-08 | Southern Illinois (107) | 83 | 73 | Southeast Missouri State (274) | Final | W | 10 |
| 11 | 2018-12-12 | Murray State (83) | 80 | 52 | Southern Illinois (82) | Final | L | -28 |
| 12 | 2018-12-15 | Southern Illinois (82) | 65 | 73 | Buffalo (12) | Final | L | -8 |
| 13 | 2018-12-22 | Winthrop (201) | 79 | 71 | Southern Illinois (108) | Final | L | -8 |
| 14 | 2019-01-02 | Missouri State (209) | 70 | 75 | Southern Illinois (140) | Final | W | 5 |
| 15 | 2019-01-05 | Southern Illinois (140) | 58 | 51 | Northern Iowa (233) | Final | W | 7 |
| 16 | 2019-01-08 | Southern Illinois (122) | 70 | 82 | Drake (105) | Final | L | -12 |
| 17 | 2019-01-12 | Valparaiso (175) | 65 | 61 | Southern Illinois (122) | Final | L | -4 |
| 18 | 2019-01-15 | Southern Illinois (143) | 58 | 59 | Illinois State (176) | Final | L | -1 |
| 19 | 2019-01-20 | Bradley (227) | 57 | 54 | Southern Illinois (143) | Final | L | -3 |
| 20 | 2019-01-23 | Northern Iowa (198) | 62 | 70 | Southern Illinois (162) | Final | W | 8 |
| 21 | 2019-01-27 | Southern Illinois (162) | 50 | 75 | Loyola-Chicago (106) | Final | L | -25 |
| 22 | 2019-01-30 | Indiana State (168) | 73 | 88 | Southern Illinois (166) | Final | W | 15 |
| 23 | 2019-02-02 | Southern Illinois (166) | 72 | 68 | Bradley (213) | Final | W | 4 |
| 24 | 2019-02-06 | Southern Illinois (157) | 59 | 65 | Missouri State (188) | Final | L | -6 |
| 25 | 2019-02-09 | Evansville (202) | 73 | 78 | Southern Illinois (157) | Final | W | 5 |
| 26 | 2019-02-12 | Drake (110) | 72 | 69 | Southern Illinois (153) | Final | L | -3 |
| 27 | 2019-02-16 | Southern Illinois (153) | 79 | 57 | Indiana State (181) | Final | W | 22 |
| 28 | 2019-02-20 | Southern Illinois (147) | 52 | 55 | Valparaiso (192) | Final | L | -3 |
| 29 | 2019-02-24 | Loyola-Chicago (129) | 53 | 63 | Southern Illinois (147) | Final | W | 10 |
| 30 | 2019-02-27 | Southern Illinois (149) | 98 | 91 | Evansville (240) | Final | W | 7 |
| 31 | 2019-03-02 | Illinois State (168) | 63 | 72 | Southern Illinois (149) | Final | W | 9 |
| 32 | 2019-03-08 | Northern Iowa (183) | 61 | 58 | Southern Illinois (138) | Final | L | -3 |