Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2024-11-04 | South Carolina Upstate (293) | 66 | 97 | North Carolina State (44) | Final | L | -31 |
| 2 | 2024-11-06 | Piedmont | 70 | 103 | South Carolina Upstate (293) | Final | W | 33 |
| 3 | 2024-11-08 | South Carolina Upstate (326) | 74 | 93 | Virginia Tech (34) | Final | L | -19 |
| 4 | 2024-11-13 | South Carolina Upstate (294) | 80 | 85 | Wake Forest (31) | Final | L | -5 |
| 5 | 2024-11-15 | UNC-Wilmington (78) | 89 | 85 | South Carolina Upstate (311) | Final | L | -4 |
| 6 | 2024-11-19 | Southern Wesleyan | 63 | 95 | South Carolina Upstate (309) | Final | W | 32 |
| 7 | 2024-11-22 | South Carolina Upstate (337) | 76 | 87 | East Tennessee State (246) | Final | L | -11 |
| 8 | 2024-11-23 | South Carolina Upstate (293) | 74 | 98 | Queens (163) | Final | L | -24 |
| 9 | 2024-11-26 | South Carolina Upstate (346) | 77 | 110 | Iowa (24) | Final | L | -33 |
| 10 | 2024-11-30 | South Carolina Upstate (351) | 51 | 73 | Coastal Carolina (258) | Final | L | -22 |
| 11 | 2024-12-04 | Brevard | 60 | 91 | South Carolina Upstate (352) | Final | W | 31 |
| 12 | 2024-12-07 | South Carolina Upstate (341) | 74 | 68 | Western Carolina (328) | Final | W | 6 |
| 13 | 2024-12-14 | South Carolina Upstate (344) | 53 | 73 | South Carolina (90) | Final | L | -20 |
| 14 | 2024-12-18 | South Carolina State (250) | 85 | 70 | South Carolina Upstate (341) | Final | L | -15 |
| 15 | 2024-12-21 | Youngstown State (193) | 72 | 64 | South Carolina Upstate (344) | Final | L | -8 |
| 16 | 2025-01-02 | South Carolina Upstate (348) | 76 | 95 | Winthrop (133) | Final | L | -19 |
| 17 | 2025-01-08 | Presbyterian (274) | 67 | 77 | South Carolina Upstate (339) | Final | W | 10 |
| 18 | 2025-01-11 | Radford (130) | 80 | 67 | South Carolina Upstate (335) | Final | L | -13 |
| 19 | 2025-01-15 | South Carolina Upstate (337) | 92 | 93 | UNC-Asheville (176) | Final | L | -1 |
| 20 | 2025-01-18 | South Carolina Upstate (340) | 68 | 97 | Gardner-Webb (228) | Final | L | -29 |
| 21 | 2025-01-22 | High Point (99) | 86 | 77 | South Carolina Upstate (339) | Final | L | -9 |
| 22 | 2025-01-25 | South Carolina Upstate (342) | 54 | 80 | Longwood (141) | Final | L | -26 |
| 23 | 2025-01-29 | Charleston Southern (303) | 82 | 75 | South Carolina Upstate (348) | Final | L | -7 |
| 24 | 2025-02-01 | South Carolina Upstate (351) | 69 | 79 | Radford (160) | Final | L | -10 |
| 25 | 2025-02-05 | South Carolina Upstate (352) | 64 | 75 | Presbyterian (270) | Final | L | -11 |
| 26 | 2025-02-08 | Winthrop (161) | 105 | 95 | South Carolina Upstate (353) | Final | L | -10 |
| 27 | 2025-02-12 | UNC-Asheville (134) | 92 | 85 | South Carolina Upstate (352) | Final | L | -7 |
| 28 | 2025-02-15 | Gardner-Webb (244) | 96 | 87 | South Carolina Upstate (351) | Final | L | -9 |
| 29 | 2025-02-22 | South Carolina Upstate (346) | 79 | 69 | Charleston Southern (295) | Final | W | 10 |
| 30 | 2025-02-26 | South Carolina Upstate (347) | 66 | 88 | High Point (79) | Final | L | -22 |
| 31 | 2025-03-01 | Longwood (269) | 83 | 66 | South Carolina Upstate (293) | Final | L | -17 |
| 32 | 2025-03-05 | South Carolina Upstate (348) | 63 | 83 | Gardner-Webb (264) | Final | L | -20 |