Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Siena (166) | 75 | 68 | Holy Cross (327) | Final | W | 7 |
| 2 | 2022-11-12 | Albany (349) | 62 | 75 | Siena (166) | Final | W | 13 |
| 3 | 2022-11-16 | Army (258) | 96 | 94 | Siena (166) | Final | L | -2 |
| 4 | 2022-11-20 | Siena (166) | 59 | 69 | Harvard (183) | Final | L | -10 |
| 5 | 2022-11-24 | Florida State (209) | 63 | 80 | Siena (166) | Final | W | 17 |
| 6 | 2022-11-25 | Siena (166) | 62 | 74 | Ole Miss (128) | Final | L | -12 |
| 7 | 2022-11-27 | Siena (166) | 60 | 55 | Seton Hall (73) | Final | W | 5 |
| 8 | 2022-12-02 | Canisius (308) | 70 | 74 | Siena (166) | Final | W | 4 |
| 9 | 2022-12-07 | Siena (166) | 68 | 75 | Georgetown (215) | Final | L | -7 |
| 10 | 2022-12-11 | Siena (166) | 64 | 75 | Delaware (220) | Final | L | -11 |
| 11 | 2022-12-19 | St. Bonaventure (146) | 70 | 76 | Siena (160) | Final | W | 6 |
| 12 | 2022-12-22 | Siena (160) | 64 | 61 | American (249) | Final | W | 3 |
| 13 | 2022-12-30 | Siena (166) | 83 | 76 | Quinnipiac (150) | Final | W | 7 |
| 14 | 2023-01-01 | Siena (166) | 70 | 61 | Fairfield (252) | Final | W | 9 |
| 15 | 2023-01-06 | Saint Peter's (292) | 60 | 70 | Siena (166) | Final | W | 10 |
| 16 | 2023-01-08 | Rider (201) | 63 | 68 | Siena (166) | Final | W | 5 |
| 17 | 2023-01-13 | Siena (166) | 70 | 64 | Niagara (229) | Final | W | 6 |
| 18 | 2023-01-15 | Siena (166) | 62 | 66 | Canisius (308) | Final | L | -4 |
| 19 | 2023-01-20 | Mount St Mary's (303) | 57 | 72 | Siena (166) | Final | W | 15 |
| 20 | 2023-01-22 | Fairfield (252) | 62 | 52 | Siena (166) | Final | L | -10 |
| 21 | 2023-01-27 | Iona (84) | 53 | 70 | Siena (166) | Final | W | 17 |
| 22 | 2023-01-29 | Siena (166) | 70 | 55 | Marist (309) | Final | W | 15 |
| 23 | 2023-02-03 | Siena (166) | 66 | 71 | Manhattan (279) | Final | L | -5 |
| 24 | 2023-02-05 | Niagara (229) | 56 | 54 | Siena (166) | Final | L | -2 |
| 25 | 2023-02-10 | Siena (166) | 72 | 65 | Mount St Mary's (303) | Final | W | 7 |
| 26 | 2023-02-12 | Marist (309) | 65 | 73 | Siena (166) | Final | W | 8 |
| 27 | 2023-02-17 | Quinnipiac (150) | 66 | 63 | Siena (166) | Final | L | -3 |
| 28 | 2023-02-24 | Siena (178) | 66 | 69 | Rider (197) | Final | L | -3 |
| 29 | 2023-02-26 | Siena (185) | 60 | 93 | Iona (77) | Final | L | -33 |
| 30 | 2023-03-02 | Manhattan (307) | 67 | 66 | Siena (160) | Final | L | -1 |
| 31 | 2023-03-04 | Siena (160) | 72 | 73 | Saint Peter's (200) | Final/OT | L | -1 |
| 32 | 2023-03-09 | Niagara (234) | 71 | 65 | Siena (220) | Final | L | -6 |