Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-11-04 | Evansville (239) | 51 | 82 | Purdue (17) | Final | W | 31 |
| 2 | 2025-11-07 | Oakland (189) | 77 | 87 | Purdue (17) | Final | W | 10 |
| 3 | 2025-11-13 | Purdue (17) | 87 | 80 | Alabama (6) | Final | W | 7 |
| 4 | 2025-11-16 | Akron (80) | 79 | 97 | Purdue (17) | Final | W | 18 |
| 5 | 2025-11-20 | Memphis (29) | 71 | 80 | Purdue (17) | Final | W | 9 |
| 6 | 2025-11-21 | Texas Tech (10) | 56 | 86 | Purdue (17) | Final | W | 30 |
| 7 | 2025-11-28 | Eastern Illinois (317) | 62 | 109 | Purdue (17) | Final | W | 47 |
| 8 | 2025-12-02 | Purdue (3) | 81 | 65 | Rutgers (146) | Final | W | 16 |
| 9 | 2025-12-06 | Iowa State (12) | 81 | 58 | Purdue (3) | Final | L | -23 |
| 10 | 2025-12-10 | Minnesota (153) | 57 | 85 | Purdue (9) | Final | W | 28 |
| 11 | 2025-12-13 | Marquette (176) | 59 | 79 | Purdue (9) | Final | W | 20 |
| 12 | 2025-12-20 | Auburn (31) | 60 | 88 | Purdue (10) | Final | W | 28 |
| 13 | 2025-12-29 | Kent State (70) | 60 | 101 | Purdue (9) | Final | W | 41 |
| 14 | 2026-01-03 | Purdue (9) | 89 | 73 | Wisconsin (75) | Final | W | 16 |
| 15 | 2026-01-07 | Washington | Purdue | Scheduled – 8:30 PM | – | – | ||
| 16 | 2026-01-10 | Penn State | Purdue | Scheduled – 2:00 PM | – | – | ||
| 17 | 2026-01-14 | Iowa | Purdue | Scheduled – 6:30 PM | – | – | ||
| 18 | 2026-01-17 | Purdue | USC | Scheduled – 3:00 PM | – | – | ||
| 19 | 2026-01-20 | Purdue | UCLA | Scheduled – 7:00 PM | – | – | ||
| 20 | 2026-01-24 | Illinois | Purdue | Scheduled – 3:00 PM | – | – | ||
| 21 | 2026-01-27 | Purdue | Indiana | Scheduled – 9:00 PM | – | – | ||
| 22 | 2026-02-01 | Purdue | Maryland | Scheduled – 1:00 PM | – | – | ||
| 23 | 2026-02-07 | Oregon | Purdue | Scheduled – 1:00 PM | – | – | ||
| 24 | 2026-02-10 | Purdue | Nebraska | Scheduled – 6:00 PM | – | – | ||
| 25 | 2026-02-13 | Purdue | Iowa | Scheduled – 11:00 PM | – | – | ||
| 26 | 2026-02-17 | Michigan | Purdue | Scheduled – 6:30 PM | – | – | ||
| 27 | 2026-02-20 | Indiana | Purdue | Scheduled – 8:00 PM | – | – | ||
| 28 | 2026-02-26 | Michigan State | Purdue | Scheduled – 8:00 PM | – | – | ||
| 29 | 2026-03-01 | Purdue | Ohio State | Scheduled – 1:30 PM | – | – | ||
| 30 | 2026-03-04 | Purdue | Northwestern | Scheduled – 7:30 PM | – | – | ||
| 31 | 2026-03-07 | Wisconsin | Purdue | Scheduled – 4:00 PM | – | – |