Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-11-06 | Fairfield (204) | 57 | 90 | Purdue (8) | Final | W | 33 |
| 2 | 2018-11-10 | Ball State (156) | 75 | 84 | Purdue (6) | Final | W | 9 |
| 3 | 2018-11-15 | Purdue (3) | 92 | 70 | Appalachian State (213) | Final | W | 22 |
| 4 | 2018-11-16 | Purdue (3) | 79 | 58 | Davidson (26) | Final | W | 21 |
| 5 | 2018-11-18 | Virginia Tech (91) | 89 | 83 | Purdue (3) | Final | L | -6 |
| 6 | 2018-11-23 | Robert Morris (240) | 46 | 84 | Purdue (22) | Final | W | 38 |
| 7 | 2018-11-28 | Purdue (25) | 72 | 73 | Florida State (32) | Final | L | -1 |
| 8 | 2018-12-01 | Purdue (25) | 57 | 76 | Michigan (5) | Final | L | -19 |
| 9 | 2018-12-06 | Maryland (22) | 60 | 62 | Purdue (43) | Final | W | 2 |
| 10 | 2018-12-09 | Purdue (43) | 68 | 72 | Texas (40) | Final | L | -4 |
| 11 | 2018-12-15 | Purdue (41) | 80 | 88 | Notre Dame (69) | Final | L | -8 |
| 12 | 2018-12-20 | Ohio (110) | 67 | 95 | Purdue (54) | Final | W | 28 |
| 13 | 2018-12-29 | Belmont (34) | 62 | 73 | Purdue (52) | Final | W | 11 |
| 14 | 2019-01-03 | Iowa (29) | 70 | 86 | Purdue (41) | Final | W | 16 |
| 15 | 2019-01-08 | Purdue (32) | 59 | 77 | Michigan State (7) | Final | L | -18 |
| 16 | 2019-01-11 | Purdue (32) | 84 | 80 | Wisconsin (25) | Final/OT | W | 4 |
| 17 | 2019-01-15 | Rutgers (98) | 54 | 89 | Purdue (29) | Final | W | 35 |
| 18 | 2019-01-19 | Indiana (23) | 55 | 70 | Purdue (29) | Final | W | 15 |
| 19 | 2019-01-23 | Purdue (22) | 79 | 67 | Ohio State (36) | Final | W | 12 |
| 20 | 2019-01-27 | Michigan State (5) | 63 | 73 | Purdue (22) | Final | W | 10 |
| 21 | 2019-01-31 | Purdue (15) | 99 | 90 | Penn State (122) | Final/OT | W | 9 |
| 22 | 2019-02-03 | Minnesota (35) | 63 | 73 | Purdue (15) | Final | W | 10 |
| 23 | 2019-02-09 | Nebraska (47) | 62 | 81 | Purdue (14) | Final | W | 19 |
| 24 | 2019-02-12 | Purdue (12) | 56 | 70 | Maryland (25) | Final | L | -14 |
| 25 | 2019-02-16 | Penn State (115) | 64 | 76 | Purdue (12) | Final | W | 12 |
| 26 | 2019-02-19 | Purdue (15) | 48 | 46 | Indiana (57) | Final | W | 2 |
| 27 | 2019-02-23 | Purdue (15) | 75 | 72 | Nebraska (44) | Final | W | 3 |
| 28 | 2019-02-27 | Illinois (94) | 56 | 73 | Purdue (14) | Final | W | 17 |
| 29 | 2019-03-02 | Ohio State (37) | 51 | 86 | Purdue (14) | Final | W | 35 |
| 30 | 2019-03-05 | Purdue (13) | 69 | 73 | Minnesota (43) | Final | L | -4 |
| 31 | 2019-03-09 | Purdue (13) | 70 | 57 | Northwestern (99) | Final | W | 13 |
| 32 | 2019-03-15 | Minnesota (41) | 75 | 73 | Purdue (14) | Final | L | -2 |
| 33 | 2019-03-21 | Old Dominion (85) | 48 | 61 | Purdue (15) | Final | W | 13 |
| 34 | 2019-03-23 | Villanova (25) | 61 | 87 | Purdue (15) | Final | W | 26 |
| 35 | 2019-03-28 | Purdue (15) | 99 | 94 | Tennessee (5) | Final/OT | W | 5 |
| 36 | 2019-03-30 | Purdue (15) | 75 | 80 | Virginia (1) | Final/OT | L | -5 |