Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2024-11-04 | Penn (131) | 58 | 57 | NJIT (306) | Final | W | 1 |
| 2 | 2024-11-07 | Maryland-Eastern Shore (353) | 84 | 85 | Penn (131) | Final | W | 1 |
| 3 | 2024-11-12 | Penn (233) | 63 | 65 | Lafayette (231) | Final | L | -2 |
| 4 | 2024-11-15 | Saint Joseph's (107) | 86 | 69 | Penn (279) | Final | L | -17 |
| 5 | 2024-11-19 | Penn (326) | 49 | 93 | Villanova (172) | Final | L | -44 |
| 6 | 2024-11-29 | Navy (296) | 86 | 78 | Penn (335) | Final | L | -8 |
| 7 | 2024-11-30 | Maine (221) | 64 | 77 | Penn (307) | Final | W | 13 |
| 8 | 2024-12-01 | Elon (159) | 68 | 53 | Penn (323) | Final | L | -15 |
| 9 | 2024-12-07 | Penn (322) | 47 | 60 | Drexel (196) | Final | L | -13 |
| 10 | 2024-12-09 | Penn (323) | 47 | 66 | Virginia Commonwealth (79) | Final | L | -19 |
| 11 | 2024-12-20 | Rider (318) | 66 | 79 | Penn (304) | Final | W | 13 |
| 12 | 2024-12-22 | Penn (317) | 53 | 85 | George Mason (114) | Final | L | -32 |
| 13 | 2024-12-29 | Penn (318) | 66 | 86 | Penn State (42) | Final | L | -20 |
| 14 | 2025-01-11 | Penn (321) | 70 | 73 | Dartmouth (238) | Final | L | -3 |
| 15 | 2025-01-18 | Cornell (140) | 86 | 76 | Penn (325) | Final | L | -10 |
| 16 | 2025-01-20 | Penn (308) | 82 | 67 | Harvard (285) | Final | W | 15 |
| 17 | 2025-01-25 | Columbia (190) | 78 | 93 | Penn (279) | Final | W | 15 |
| 18 | 2025-01-31 | Brown (207) | 88 | 79 | Penn (289) | Final | L | -9 |
| 19 | 2025-02-01 | Yale (92) | 90 | 61 | Penn (296) | Final | L | -29 |
| 20 | 2025-02-07 | Princeton (122) | 61 | 59 | Penn (302) | Final | L | -2 |
| 21 | 2025-02-14 | Penn (301) | 71 | 72 | Yale (88) | Final | L | -1 |
| 22 | 2025-02-15 | Penn (309) | 72 | 82 | Brown (205) | Final | L | -10 |
| 23 | 2025-02-21 | Dartmouth (207) | 75 | 88 | Penn (293) | Final | W | 13 |
| 24 | 2025-02-22 | Harvard (264) | 79 | 78 | Penn (301) | Final (OT) | L | -1 |
| 25 | 2025-02-28 | Penn (304) | 62 | 90 | Cornell (159) | Final | L | -28 |
| 26 | 2025-03-01 | Penn (131) | 92 | 87 | Columbia (193) | Final | W | 5 |
| 27 | 2025-03-08 | Penn (296) | 71 | 95 | Princeton (149) | Final | L | -24 |